Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB3N51_RS08965 Genome accession   NZ_CP162190
Coordinates   1841636..1842292 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain STK77-E     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1836636..1847292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3N51_RS08935 (AB3N51_08935) yecA 1837888..1838553 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  AB3N51_RS08955 (AB3N51_08955) pgsA 1839202..1839750 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB3N51_RS08960 (AB3N51_08960) uvrC 1839807..1841639 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  AB3N51_RS08965 (AB3N51_08965) letA 1841636..1842292 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AB3N51_RS08970 (AB3N51_08970) - 1842434..1842550 (+) 117 WP_001302039.1 hypothetical protein -
  AB3N51_RS08975 (AB3N51_08975) yecU 1842588..1842764 (+) 177 WP_000590344.1 protein YecU -
  AB3N51_RS08980 (AB3N51_08980) yecF 1842751..1842975 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  AB3N51_RS08985 (AB3N51_08985) sdiA 1843043..1843765 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  AB3N51_RS08990 (AB3N51_08990) tcyN 1843995..1844747 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AB3N51_RS08995 (AB3N51_08995) tcyL 1844744..1845412 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  AB3N51_RS09000 (AB3N51_09000) dcyD 1845427..1846413 (-) 987 WP_001128227.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=920562 AB3N51_RS08965 WP_000611328.1 1841636..1842292(-) (letA) [Escherichia coli strain STK77-E]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=920562 AB3N51_RS08965 WP_000611328.1 1841636..1842292(-) (letA) [Escherichia coli strain STK77-E]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482