Detailed information NTG0919949

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: VO177_RS06960
• Genome accession: NZ_CP141828
• Coordinates: 1364129..1365292 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain TZS01
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1359129..1370292

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VO177_RS06940 (VO177_06940)	tuaH	1359546..1360742 (+)	1197	WP_031304142.1	teichuronic acid biosynthesis protein TuaH	-
VO177_RS06945 (VO177_06945)	-	1360874..1361950 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
VO177_RS06950 (VO177_06950)	-	1362040..1363254 (-)	1215	WP_014419013.1	LCP family protein	-
VO177_RS06955 (VO177_06955)	-	1363259..1363906 (-)	648	WP_021494097.1	YigZ family protein	-
VO177_RS06960 (VO177_06960)	degS	1364129..1365292 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
VO177_RS06965 (VO177_06965)	degU	1365369..1366058 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
VO177_RS06970 (VO177_06970)	-	1366156..1367004 (+)	849	WP_003151387.1	DegV family protein	-
VO177_RS06975 (VO177_06975)	comFA	1367112..1368497 (+)	1386	WP_103526593.1	DEAD/DEAH box helicase	Machinery gene
VO177_RS06980 (VO177_06980)	-	1368555..1368839 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
VO177_RS06985 (VO177_06985)	comFC	1368845..1369534 (+)	690	WP_199449054.1	ComF family protein	Machinery gene
VO177_RS06990 (VO177_06990)	-	1369608..1370027 (+)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=919949 VO177_RS06960 WP_007407484.1 1364129..1365292(+) (degS) [Bacillus velezensis strain TZS01]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=919949 VO177_RS06960 WP_007407484.1 1364129..1365292(+) (degS) [Bacillus velezensis strain TZS01]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951