Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   VF946_RS07065 Genome accession   NZ_CP141824
Coordinates   1366620..1367999 (-) Length   459 a.a.
NCBI ID   WP_024383407.1    Uniprot ID   A0A0Z8JF15
Organism   Streptococcus suis strain HB18     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1361620..1372999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS07045 - 1362889..1363469 (-) 581 Protein_1360 class I SAM-dependent methyltransferase -
  VF946_RS07050 coaA 1363578..1364498 (+) 921 WP_002935283.1 type I pantothenate kinase -
  VF946_RS07055 rpsT 1364557..1364805 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  VF946_RS07060 - 1365067..1366296 (-) 1230 WP_023369936.1 transglutaminase domain-containing protein -
  VF946_RS07065 ciaH 1366620..1367999 (-) 1380 WP_024383407.1 sensor histidine kinase Regulator
  VF946_RS07070 ciaR 1367992..1368663 (-) 672 WP_024394126.1 response regulator transcription factor Regulator
  VF946_RS07075 - 1368857..1369237 (-) 381 WP_023369940.1 hypothetical protein -
  VF946_RS07080 - 1369622..1370824 (+) 1203 WP_074389402.1 IS110 family transposase -
  VF946_RS07085 phoU 1371026..1371682 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  VF946_RS07090 pstB 1371711..1372469 (-) 759 WP_329894429.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51951.68 Da        Isoelectric Point: 6.8879

>NTDB_id=919757 VF946_RS07065 WP_024383407.1 1366620..1367999(-) (ciaH) [Streptococcus suis strain HB18]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQMAANIKDKLVCFTVIDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=919757 VF946_RS07065 WP_024383407.1 1366620..1367999(-) (ciaH) [Streptococcus suis strain HB18]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAACTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGGTTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTGTCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCAGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAAGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATGGCAGCTAATATCAAGGATAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGCC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATCTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8JF15

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488