Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ABZS48_RS04385 Genome accession   NZ_CP160100
Coordinates   880913..882694 (-) Length   593 a.a.
NCBI ID   WP_000390521.1    Uniprot ID   -
Organism   Staphylococcus aureus strain A_01_sau     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 875913..887694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABZS48_RS04365 (ABZS48_04370) racE 876302..877102 (-) 801 WP_001039660.1 glutamate racemase -
  ABZS48_RS04370 (ABZS48_04375) sdhB 877342..878157 (-) 816 WP_000132057.1 succinate dehydrogenase iron-sulfur subunit -
  ABZS48_RS04375 (ABZS48_04380) sdhA 878157..879923 (-) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  ABZS48_RS04380 (ABZS48_04385) - 879975..880589 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  ABZS48_RS04385 (ABZS48_04390) uvrC 880913..882694 (-) 1782 WP_000390521.1 excinuclease ABC subunit UvrC Machinery gene
  ABZS48_RS04390 (ABZS48_04395) - 882885..882956 (+) 72 WP_223200532.1 hypothetical protein -
  ABZS48_RS04395 (ABZS48_04400) trxA 883019..883333 (-) 315 WP_001018928.1 thioredoxin -
  ABZS48_RS04400 (ABZS48_04405) mutS/mutS2 883506..885854 (-) 2349 WP_001249279.1 endonuclease MutS2 Machinery gene
  ABZS48_RS04405 (ABZS48_04410) polX 885864..887576 (-) 1713 WP_000161953.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68653.34 Da        Isoelectric Point: 9.7443

>NTDB_id=916797 ABZS48_RS04385 WP_000390521.1 880913..882694(-) (uvrC) [Staphylococcus aureus strain A_01_sau]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRHFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKEMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFIDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNLGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=916797 ABZS48_RS04385 WP_000390521.1 880913..882694(-) (uvrC) [Staphylococcus aureus strain A_01_sau]
TTGGAAGATTATAAACAACGAATTAAAAATAAATTAAATGTTGTACCTATGGAACCGGGTTGCTATTTAATGAAAGACCG
CAATGATCAAGTGATATATGTTGGGAAAGCTAAAAAATTAAGAAATCGATTACGATCATATTTTACGGGCGCACACGATG
CTAAAACAACGAGACTTGTTGGAGAAATACGGCATTTTGAATTTATTGTCACATCTAGTGAAACAGAGTCATTATTACTT
GAATTAAATTTGATCAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGTTGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAACGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTGCCGCGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGAGATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCAATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTATCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGCCGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACCGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATTTAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565