Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   U2H13_RS12190 Genome accession   NZ_CP141181
Coordinates   2514446..2515516 (-) Length   356 a.a.
NCBI ID   WP_014418378.1    Uniprot ID   A0AAP4DGV9
Organism   Bacillus sp. A1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2509446..2520516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2H13_RS12140 (U2H13_12125) sipW 2509505..2510089 (-) 585 WP_012117977.1 signal peptidase I SipW -
  U2H13_RS12145 (U2H13_12130) tapA 2510061..2510732 (-) 672 WP_025649852.1 amyloid fiber anchoring/assembly protein TapA -
  U2H13_RS12150 (U2H13_12135) - 2510991..2511320 (+) 330 WP_012117979.1 DUF3889 domain-containing protein -
  U2H13_RS12155 (U2H13_12140) - 2511361..2511540 (-) 180 WP_003153093.1 YqzE family protein -
  U2H13_RS12160 (U2H13_12145) comGG 2511597..2511974 (-) 378 WP_017418138.1 competence type IV pilus minor pilin ComGG Machinery gene
  U2H13_RS12165 (U2H13_12150) comGF 2511975..2512370 (-) 396 WP_025649850.1 competence type IV pilus minor pilin ComGF -
  U2H13_RS12170 (U2H13_12155) comGE 2512384..2512698 (-) 315 WP_017418140.1 competence type IV pilus minor pilin ComGE Machinery gene
  U2H13_RS12175 (U2H13_12160) comGD 2512682..2513119 (-) 438 WP_095061019.1 competence type IV pilus minor pilin ComGD Machinery gene
  U2H13_RS12180 (U2H13_12165) comGC 2513109..2513417 (-) 309 WP_014418376.1 competence type IV pilus major pilin ComGC Machinery gene
  U2H13_RS12185 (U2H13_12170) comGB 2513422..2514459 (-) 1038 WP_088461121.1 competence type IV pilus assembly protein ComGB Machinery gene
  U2H13_RS12190 (U2H13_12175) comGA 2514446..2515516 (-) 1071 WP_014418378.1 competence type IV pilus ATPase ComGA Machinery gene
  U2H13_RS12195 (U2H13_12180) - 2515709..2516659 (-) 951 WP_014418379.1 magnesium transporter CorA family protein -
  U2H13_RS12200 (U2H13_12185) - 2516805..2518106 (+) 1302 WP_029973873.1 hemolysin family protein -
  U2H13_RS12205 (U2H13_12190) - 2518144..2518974 (-) 831 WP_021494316.1 STAS domain-containing protein -
  U2H13_RS12215 (U2H13_12200) - 2519181..2519561 (-) 381 WP_003153079.1 Spx/MgsR family RNA polymerase-binding regulatory protein -
  U2H13_RS12220 (U2H13_12205) - 2519798..2520043 (+) 246 WP_003153078.1 DUF2626 domain-containing protein -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 40529.81 Da        Isoelectric Point: 9.3485

>NTDB_id=916257 U2H13_RS12190 WP_014418378.1 2514446..2515516(-) (comGA) [Bacillus sp. A1]
MKNIETYSRNIINEAYTARASDIHIVPRERDAFIHFRIGHALVKKRVLKKEECVRLISHFKFLSAMDIGERRKPQNGSLS
LPLPTETVHLRMSTLPTMNDESLVIRLLPKQQIPPLDKLSLFRGAGAALLSFLKHSHGLLLFTGPTGSGKTTTLYSLVNY
AKRHFNRRIVTLEDPVETRDEDVLQVQVNEKAGVTYSAGLKAILRHDPDMIILGEIRDAETAEIAVRAAMTGHLVLSSLH
TRDAKGAIYRLLEFGVNMTEIEQTVIAIAAQRLVDLTCPFCKEENCSVYCRMYRQTRRAGIYELLYGKNLTQCFQEAKGE
HANFQYQTLRRLIRKGIALGYVTTDNYDRWVYHEAD

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=916257 U2H13_RS12190 WP_014418378.1 2514446..2515516(-) (comGA) [Bacillus sp. A1]
GTGAAAAATATTGAAACATACAGCAGGAACATCATAAACGAGGCCTATACGGCAAGGGCTTCAGATATACACATTGTGCC
GAGAGAAAGGGATGCTTTCATTCATTTTCGCATCGGCCATGCTCTTGTGAAAAAAAGAGTCTTAAAAAAAGAGGAATGTG
TAAGGCTTATTTCTCATTTCAAGTTTTTATCGGCCATGGATATAGGAGAAAGACGAAAGCCGCAAAACGGGTCATTGTCT
CTGCCGCTTCCGACAGAAACCGTTCATTTGAGAATGTCAACCTTGCCGACAATGAATGATGAAAGTCTTGTCATCAGGCT
TTTGCCTAAGCAGCAGATTCCCCCTCTGGATAAACTGTCCTTATTTCGGGGGGCAGGCGCCGCACTATTGTCCTTTCTGA
AGCATTCGCACGGCCTGCTTCTGTTTACCGGCCCGACCGGATCTGGAAAAACGACCACTCTTTACTCGCTTGTCAACTAT
GCAAAACGGCATTTCAACCGGCGGATTGTCACGCTTGAAGACCCCGTAGAAACAAGAGATGAGGATGTGCTGCAAGTTCA
GGTGAATGAAAAAGCCGGAGTCACATATTCCGCCGGTTTAAAAGCGATTTTAAGACATGATCCCGATATGATCATCTTAG
GGGAAATCAGGGATGCCGAGACGGCTGAAATCGCAGTCCGCGCGGCAATGACGGGACACCTCGTTCTTTCAAGCCTGCAT
ACAAGAGATGCTAAGGGCGCCATATACAGGCTGCTGGAGTTTGGCGTGAACATGACAGAAATTGAACAAACCGTCATTGC
CATTGCCGCTCAGCGTCTGGTTGATTTAACATGTCCGTTCTGCAAAGAGGAAAACTGTTCCGTGTACTGCCGGATGTACA
GGCAGACACGCCGTGCGGGCATTTATGAACTGCTCTACGGGAAAAACCTCACCCAATGCTTTCAGGAAGCAAAGGGAGAG
CACGCCAATTTTCAATATCAGACGCTCCGCAGGCTGATCAGAAAAGGAATCGCGCTCGGCTATGTCACGACCGACAATTA
CGATCGGTGGGTGTATCATGAAGCGGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-275)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Bacillus subtilis subsp. subtilis str. 168

82.303

100

0.823
  pilB Glaesserella parasuis strain SC1401

38.793

97.753

0.379
  pilF Thermus thermophilus HB27

37.892

98.596

0.374