Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABXJ10_RS13605 Genome accession   NZ_CP159639
Coordinates   2800338..2800994 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z226-7     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2795338..2805994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXJ10_RS13575 (ABXJ10_13575) yecA 2796589..2797254 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ABXJ10_RS13595 (ABXJ10_13595) pgsA 2797904..2798452 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABXJ10_RS13600 (ABXJ10_13600) uvrC 2798509..2800341 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ABXJ10_RS13605 (ABXJ10_13605) letA 2800338..2800994 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABXJ10_RS13610 (ABXJ10_13610) - 2801136..2801252 (+) 117 WP_001302039.1 hypothetical protein -
  ABXJ10_RS13615 (ABXJ10_13615) yecU 2801290..2801466 (+) 177 WP_000590347.1 protein YecU -
  ABXJ10_RS13620 (ABXJ10_13620) yecF 2801453..2801677 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABXJ10_RS13625 (ABXJ10_13625) sdiA 2801745..2802467 (-) 723 WP_001154287.1 transcriptional regulator SdiA -
  ABXJ10_RS13630 (ABXJ10_13630) tcyN 2802697..2803449 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABXJ10_RS13635 (ABXJ10_13635) tcyL 2803446..2804114 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ABXJ10_RS13640 (ABXJ10_13640) dcyD 2804129..2805115 (-) 987 WP_001128213.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=913659 ABXJ10_RS13605 WP_000611335.1 2800338..2800994(-) (letA) [Escherichia coli strain Z226-7]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=913659 ABXJ10_RS13605 WP_000611335.1 2800338..2800994(-) (letA) [Escherichia coli strain Z226-7]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486