Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AABK05_RS01905 Genome accession   NZ_AP027877
Coordinates   419574..420206 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2018-05-2CC     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 414574..425206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABK05_RS01880 (VEE46_03690) yhfG 414705..414872 (+) 168 WP_338388031.1 YhfG family protein -
  AABK05_RS01885 (VEE46_03700) fic 414862..415464 (+) 603 WP_240767649.1 putative adenosine monophosphate-protein transferase Fic -
  AABK05_RS01890 (VEE46_03710) pabA 415496..416059 (+) 564 WP_000601848.1 aminodeoxychorismate synthase component 2 -
  AABK05_RS01895 (VEE46_03720) argD 416146..417366 (+) 1221 WP_338388032.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AABK05_RS01900 (VEE46_03730) yhfK 417433..419523 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AABK05_RS01905 (VEE46_03740) crp 419574..420206 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AABK05_RS01910 (VEE46_03750) yhfA 420508..420912 (+) 405 WP_001148908.1 OsmC family protein -
  AABK05_RS01915 (VEE46_03760) prkB 420967..421836 (-) 870 WP_001274675.1 phosphoribulokinase -
  AABK05_RS01920 (VEE46_03770) yheU 421890..422108 (-) 219 WP_000907085.1 YheU family protein -
  AABK05_RS01925 (VEE46_03780) yheT 422102..423124 (-) 1023 WP_215261784.1 hydrolase -
  AABK05_RS01930 (VEE46_03790) yheS 423124..425037 (-) 1914 WP_338388033.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=91328 AABK05_RS01905 WP_000242755.1 419574..420206(-) (crp) [Escherichia coli strain 2018-05-2CC]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=91328 AABK05_RS01905 WP_000242755.1 419574..420206(-) (crp) [Escherichia coli strain 2018-05-2CC]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTTTGCTGAACCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment