Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   U0N78_RS05075 Genome accession   NZ_CP140109
Coordinates   1049861..1051240 (+) Length   459 a.a.
NCBI ID   WP_043025694.1    Uniprot ID   A0A0Z8EFB3
Organism   Streptococcus suis strain 2022WUSS148     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1044861..1056240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS05045 (U0N78_05045) pstA 1045303..1046190 (+) 888 WP_029178759.1 phosphate ABC transporter permease PstA -
  U0N78_RS05050 (U0N78_05050) pstB 1046215..1047018 (+) 804 WP_174850197.1 phosphate ABC transporter ATP-binding protein PstB -
  U0N78_RS05055 (U0N78_05055) pstB 1047030..1047788 (+) 759 WP_043024749.1 phosphate ABC transporter ATP-binding protein PstB -
  U0N78_RS05060 (U0N78_05060) phoU 1047817..1048473 (+) 657 WP_043033622.1 phosphate signaling complex protein PhoU -
  U0N78_RS05065 (U0N78_05065) - 1048622..1049002 (+) 381 WP_043025691.1 hypothetical protein -
  U0N78_RS05070 (U0N78_05070) ciaR 1049197..1049868 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  U0N78_RS05075 (U0N78_05075) ciaH 1049861..1051240 (+) 1380 WP_043025694.1 sensor histidine kinase Regulator
  U0N78_RS05080 (U0N78_05080) - 1051341..1052570 (+) 1230 WP_197315161.1 transglutaminase domain-containing protein -
  U0N78_RS05085 (U0N78_05085) rpsT 1052786..1053034 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  U0N78_RS05090 (U0N78_05090) coaA 1053093..1054013 (-) 921 WP_197315162.1 type I pantothenate kinase -
  U0N78_RS05095 (U0N78_05095) - 1054122..1054712 (+) 591 WP_074411948.1 class I SAM-dependent methyltransferase -
  U0N78_RS05100 (U0N78_05100) - 1054709..1055986 (+) 1278 WP_024413752.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51868.58 Da        Isoelectric Point: 6.8979

>NTDB_id=912586 U0N78_RS05075 WP_043025694.1 1049861..1051240(+) (ciaH) [Streptococcus suis strain 2022WUSS148]
MPKRIRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKNQKNTRGVEQLKLGINTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSIRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGKIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=912586 U0N78_RS05075 WP_043025694.1 1049861..1051240(+) (ciaH) [Streptococcus suis strain 2022WUSS148]
ATGCCTAAGCGAATCAGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGTTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAGCCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCTAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGGTGT
AGAACAGCTGAAATTAGGTATCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCTTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGCATTTACCTATCAAATCTTAGCATACGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCAGTGCTCCAAAATCGCTTGGAGAGCCTATTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCTGAAGAAAATGGAAAAACGCTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
AAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTTACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8EFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

49.89

99.129

0.495
  ciaH Streptococcus pneumoniae Rx1

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae D39

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae R6

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae TIGR4

49.563

99.782

0.495