Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   U0037_RS18850 Genome accession   NZ_CP140009
Coordinates   4169071..4171296 (-) Length   741 a.a.
NCBI ID   WP_012724912.1    Uniprot ID   C3JY32
Organism   Pseudomonas marginalis strain SBW25     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4164071..4176296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0037_RS18815 (U0037_18815) murB 4164466..4165485 (-) 1020 WP_012724906.1 UDP-N-acetylmuramate dehydrogenase -
  U0037_RS18820 (U0037_18820) - 4165482..4165946 (-) 465 WP_012724907.1 low molecular weight protein-tyrosine-phosphatase -
  U0037_RS18825 (U0037_18825) kdsB 4165946..4166710 (-) 765 WP_012724908.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  U0037_RS18830 (U0037_18830) - 4166707..4166892 (-) 186 WP_003174668.1 Trm112 family protein -
  U0037_RS18835 (U0037_18835) lpxK 4166917..4167927 (-) 1011 WP_012724909.1 tetraacyldisaccharide 4'-kinase -
  U0037_RS18840 (U0037_18840) - 4167927..4168355 (-) 429 WP_012724910.1 ExbD/TolR family protein -
  U0037_RS18845 (U0037_18845) exbB 4168352..4168987 (-) 636 WP_012724911.1 MotA/TolQ/ExbB proton channel family protein Machinery gene
  U0037_RS18850 (U0037_18850) comA 4169071..4171296 (-) 2226 WP_012724912.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  U0037_RS18855 (U0037_18855) - 4171432..4171947 (+) 516 WP_012724913.1 DUF2062 domain-containing protein -
  U0037_RS18860 (U0037_18860) - 4171964..4172148 (-) 185 Protein_3755 helix-turn-helix domain-containing protein -
  U0037_RS18865 (U0037_18865) - 4172380..4175133 (+) 2754 WP_012724914.1 response regulator -
  U0037_RS18870 (U0037_18870) - 4175225..4176214 (+) 990 WP_012724915.1 2-hydroxyacid dehydrogenase -

Sequence

Protein


Download         Length: 741 a.a.        Molecular weight: 80582.67 Da        Isoelectric Point: 10.8982

>NTDB_id=912431 U0037_RS18850 WP_012724912.1 4169071..4171296(-) (comA) [Pseudomonas marginalis strain SBW25]
MRTGMFAFALGLLALRFLPALPATGWLIALLVLALMLLPFRTYPLAFFLLGLSWACISAQWALDDRLRPALDGQTRWVEG
WVTGLPQQTGEGVRFVLTDSRSRNARLPTRIRVSWRGGPPVRSGERWRLAITLKRPAGLLNFHGFDQEAWLLAQRIGATG
TVKDGERLAPARHAWRDNVRQRLMVVDAQGREAGLMALVLGDGSGLAATDWQVLQDTGTVHLLVISGQHIGLLAGLIYGV
IAGLARYGCWPRTWPWLPWACGLAFSAALGYGVLAGFGVPVQRACVMVGLVLLWRLRFRHLGLWWPLLLALNAVLVLEPL
ASLQPGFWLSFAAVAVLVLAFGGRLGPWSLWQAWTRPQWLIAIGLFPVLLVLGLPISLSAPFANLVAVPWISLVVLPLAL
LGTALLPLPWVGDGLLWLAGGALDGLFNGLAWLAGYMPAWIPAEVPLGYWLVSLLGAVLLLLPKGVPFRLLGWPMLLLAV
FPPQERVPHGQVEVVQLDVGQGQSLILRTRHHTLLYDAGPRSGTFDLGARVVLPSLRKLGVAALDLMLLSHADADHAGGA
AAIAKGLPIKRVVGGETDGLPAFLGTRPCISGERWTWDGVTFELWQWPGAISGNPKSCVLQVQANGERLLLTGDIDRAAE
QAMLASPLAVPTEWLQAPHHGSRSSSSWAFLERLAPGSVLISRGRGNAFGHPHPQVMARYQRLGSQVYDSAEQGAVRVQL
GAFAPPVVARSQRRFWRERLP

Nucleotide


Download         Length: 2226 bp        

>NTDB_id=912431 U0037_RS18850 WP_012724912.1 4169071..4171296(-) (comA) [Pseudomonas marginalis strain SBW25]
ATGAGGACAGGGATGTTCGCGTTTGCGCTGGGGCTGCTGGCCTTGCGTTTTCTACCGGCATTGCCGGCAACCGGCTGGCT
GATCGCCCTGCTGGTGCTGGCGTTGATGCTGTTGCCGTTTCGCACTTACCCCTTGGCGTTTTTCCTGCTGGGGCTGAGTT
GGGCGTGCATCAGCGCACAGTGGGCCCTGGATGACCGCCTGCGGCCAGCGTTGGACGGCCAGACGCGTTGGGTGGAAGGG
TGGGTCACCGGTCTGCCGCAACAGACGGGCGAGGGCGTGCGTTTCGTACTGACCGACAGCCGGTCACGTAACGCGCGGTT
GCCTACACGCATCCGGGTGTCCTGGCGTGGCGGGCCGCCGGTGCGCAGCGGTGAACGCTGGCGCCTGGCGATTACTCTCA
AACGACCGGCCGGGTTGCTGAATTTCCACGGCTTTGATCAGGAAGCCTGGCTGCTGGCCCAGCGGATTGGCGCCACCGGT
ACGGTGAAGGACGGCGAGCGTCTGGCACCGGCCCGCCACGCCTGGCGTGACAACGTGCGCCAGCGCCTGATGGTGGTGGA
TGCCCAGGGCCGGGAAGCCGGCCTGATGGCCCTGGTATTGGGCGATGGTTCCGGATTGGCCGCTACCGATTGGCAGGTGT
TGCAGGACACCGGCACCGTGCATCTGCTGGTCATTTCCGGCCAGCACATCGGTTTGCTCGCGGGCTTGATCTACGGGGTG
ATCGCCGGGTTGGCGCGCTACGGCTGCTGGCCGCGAACCTGGCCGTGGCTGCCCTGGGCGTGCGGCCTGGCGTTCAGCGC
CGCGCTGGGTTACGGCGTGCTGGCAGGGTTTGGCGTGCCGGTGCAGCGCGCCTGCGTGATGGTCGGGTTGGTGTTGTTGT
GGCGCTTGCGCTTCCGGCATCTGGGGCTGTGGTGGCCATTGCTGCTGGCACTCAATGCGGTGCTGGTCCTGGAGCCGTTG
GCCAGCCTGCAGCCAGGGTTCTGGCTGTCGTTTGCGGCGGTGGCGGTGCTGGTCCTGGCGTTTGGCGGACGGCTGGGACC
GTGGAGCCTTTGGCAGGCGTGGACCCGCCCGCAGTGGTTGATTGCCATCGGGTTGTTTCCGGTCTTGCTGGTGCTGGGGC
TGCCTATCAGCCTCAGCGCACCGTTCGCTAATCTGGTTGCGGTGCCCTGGATCAGCCTGGTGGTATTGCCGCTGGCGTTG
CTGGGGACCGCGTTGCTGCCGCTGCCGTGGGTGGGTGATGGATTGCTGTGGCTGGCGGGCGGTGCGCTGGACGGCTTGTT
CAACGGCTTGGCGTGGCTGGCCGGGTACATGCCTGCCTGGATCCCGGCCGAGGTGCCGCTGGGCTACTGGCTGGTGAGTC
TGCTCGGTGCGGTGCTGCTCCTGCTGCCCAAGGGCGTGCCGTTTCGGCTGCTGGGCTGGCCGATGCTGTTACTGGCGGTG
TTTCCGCCGCAAGAACGGGTGCCCCATGGGCAGGTGGAGGTCGTGCAGCTGGACGTCGGGCAGGGACAGTCGCTGATTTT
GCGCACGCGTCACCACACTTTGCTGTATGACGCCGGTCCACGCTCCGGAACCTTTGACCTGGGCGCCCGCGTGGTGTTGC
CGTCGTTGCGAAAGCTTGGGGTAGCGGCCTTGGACCTGATGCTGCTCAGCCACGCCGACGCCGATCATGCCGGTGGTGCG
GCAGCGATTGCCAAGGGCCTGCCGATCAAGCGCGTGGTGGGTGGAGAAACCGACGGGCTGCCGGCGTTTCTCGGCACCCG
GCCGTGCATCAGTGGCGAGCGCTGGACCTGGGACGGCGTGACGTTCGAACTCTGGCAGTGGCCTGGCGCCATCAGTGGCA
ATCCGAAGTCTTGCGTGTTGCAGGTGCAGGCCAATGGCGAGCGCCTGCTGCTGACCGGCGACATTGACCGCGCCGCCGAA
CAGGCCATGCTCGCTTCCCCGCTGGCGGTGCCCACTGAATGGTTGCAAGCGCCGCACCATGGCAGTCGCAGTTCTTCGTC
GTGGGCGTTTCTGGAGCGCCTCGCCCCTGGTTCCGTGCTTATTTCACGGGGGCGGGGTAATGCGTTCGGCCATCCGCATC
CCCAGGTGATGGCGCGCTACCAGCGGTTGGGCAGCCAGGTGTATGACAGTGCCGAGCAGGGTGCTGTGCGCGTGCAATTG
GGCGCTTTCGCACCACCGGTTGTTGCGCGCAGTCAACGCAGGTTCTGGCGCGAGCGGTTACCTTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-667)

Competence protein (Competence)

(198-463)

Domain of unknown function (DUF4131) (DUF4131)

(20-167)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C3JY32

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Pseudomonas stutzeri DSM 10701

60.833

97.166

0.591
  comA Ralstonia pseudosolanacearum GMI1000

34.913

100

0.378