Detailed information NTG0911590

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: U0450_RS07245
• Genome accession: NZ_CP139863
• Coordinates: 1413501..1414568 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain 15P2112
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1408501..1419568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0450_RS07230	amiA3	1409024..1411003 (+)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator
U0450_RS07235	amiC	1411070..1412566 (+)	1497	WP_000759907.1	ABC transporter permease	Regulator
U0450_RS07240	amiD	1412566..1413492 (+)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
U0450_RS07245	amiE	1413501..1414568 (+)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
U0450_RS07250	amiF	1414579..1415505 (+)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
U0450_RS07255	-	1416124..1416933 (+)	810	Protein_1383	ABC transporter substrate-binding protein	-
U0450_RS07260	-	1416945..1417822 (+)	878	Protein_1384	ABC transporter permease	-
U0450_RS07265	-	1417835..1418638 (+)	804	WP_000157656.1	ABC transporter ATP-binding protein	-
U0450_RS07270	treR	1418671..1419381 (-)	711	WP_000760675.1	trehalose operon repressor	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=911590 U0450_RS07245 WP_000159554.1 1413501..1414568(+) (amiE) [Streptococcus pneumoniae strain 15P2112]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=911590 U0450_RS07245 WP_000159554.1 1413501..1414568(+) (amiE) [Streptococcus pneumoniae strain 15P2112]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541