Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   U0449_RS05360 Genome accession   NZ_CP139862
Coordinates   1059007..1059669 (+) Length   220 a.a.
NCBI ID   WP_000649964.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1054007..1064669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS05330 tnpB 1054444..1054767 (+) 324 WP_000586641.1 IS66 family insertion sequence element accessory protein TnpB -
  U0449_RS05335 - 1054922..1055230 (-) 309 Protein_1053 transposase -
  U0449_RS05340 - 1055203..1055741 (+) 539 Protein_1054 transposase -
  U0449_RS05345 cysK 1055816..1056736 (-) 921 WP_000029866.1 cysteine synthase A -
  U0449_RS05350 - 1057021..1057656 (-) 636 WP_000395739.1 YigZ family protein -
  U0449_RS05355 comFA/cflA 1057712..1059010 (+) 1299 WP_000867609.1 DEAD/DEAH box helicase Machinery gene
  U0449_RS05360 comFC/cflB 1059007..1059669 (+) 663 WP_000649964.1 ComF family protein Machinery gene
  U0449_RS05365 hpf 1059749..1060297 (+) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  U0449_RS05370 - 1060433..1062406 (+) 1974 WP_050205401.1 DHH family phosphoesterase -
  U0449_RS05375 rplI 1062403..1062855 (+) 453 WP_050114792.1 50S ribosomal protein L9 -
  U0449_RS05380 dnaB 1062899..1064251 (+) 1353 WP_050114789.1 replicative DNA helicase -
  U0449_RS05385 - 1064253..1064519 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25253.15 Da        Isoelectric Point: 7.3688

>NTDB_id=911485 U0449_RS05360 WP_000649964.1 1059007..1059669(+) (comFC/cflB) [Streptococcus pneumoniae strain 05H0020-2]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=911485 U0449_RS05360 WP_000649964.1 1059007..1059669(+) (comFC/cflB) [Streptococcus pneumoniae strain 05H0020-2]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAATAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909