Detailed information NTG0911406

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: U0447_RS04140
• Genome accession: NZ_CP139861
• Coordinates: 783470..784480 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 16H2017-2
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 778470..789480

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0447_RS04115	-	779500..779793 (-)	294	WP_000977368.1	hypothetical protein	-
U0447_RS04120	-	779955..780407 (+)	453	WP_000079148.1	universal stress protein	-
U0447_RS04125	-	780442..781830 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
U0447_RS04130	-	781896..782858 (+)	963	WP_044791898.1	asparaginase	-
U0447_RS04135	-	782855..783406 (-)	552	WP_219589522.1	hypothetical protein	-
U0447_RS04140	ccpA	783470..784480 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
U0447_RS04145	-	784905..785504 (-)	600	WP_000866729.1	response regulator transcription factor	-
U0447_RS04150	-	785506..786603 (-)	1098	WP_000893550.1	sensor histidine kinase	-
U0447_RS04155	-	786603..787340 (-)	738	WP_000832827.1	ABC transporter permease	-
U0447_RS04160	-	787342..788226 (-)	885	WP_050139356.1	ABC transporter ATP-binding protein	-
U0447_RS04165	-	788213..788407 (-)	195	WP_044792461.1	hypothetical protein	-
U0447_RS04170	-	788404..788610 (-)	207	Protein_801	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=911406 U0447_RS04140 WP_000990607.1 783470..784480(-) (ccpA) [Streptococcus pneumoniae strain 16H2017-2]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=911406 U0447_RS04140 WP_000990607.1 783470..784480(-) (ccpA) [Streptococcus pneumoniae strain 16H2017-2]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTATCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568