Detailed information NTG0911185

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ABQ274_RS09670
• Genome accession: NZ_CP159281
• Coordinates: 1946945..1949467 (+)
• Length: 840 a.a.
• NCBI ID: WP_353726866.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain FNZ339
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1941945..1954467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABQ274_RS09635 (ABQ274_09635)	-	1942599..1942976 (+)	378	WP_003132003.1	DUF1634 domain-containing protein	-
ABQ274_RS09645 (ABQ274_09645)	-	1943335..1943541 (+)	207	WP_023164707.1	hypothetical protein	-
ABQ274_RS09650 (ABQ274_09650)	-	1943583..1944464 (+)	882	WP_031561203.1	NAD(P)-dependent oxidoreductase	-
ABQ274_RS09655 (ABQ274_09655)	-	1944647..1945600 (-)	954	WP_010906389.1	hypothetical protein	-
ABQ274_RS09660 (ABQ274_09660)	-	1945733..1946035 (+)	303	WP_161908452.1	helix-turn-helix transcriptional regulator	-
ABQ274_RS09665 (ABQ274_09665)	-	1946404..1946751 (+)	348	WP_010906386.1	RicAFT regulatory complex protein RicA family protein	-
ABQ274_RS09670 (ABQ274_09670)	hexA	1946945..1949467 (+)	2523	WP_353726866.1	DNA mismatch repair protein MutS	Machinery gene
ABQ274_RS09675 (ABQ274_09675)	-	1949582..1950277 (+)	696	WP_010906384.1	hypothetical protein	-
ABQ274_RS09680 (ABQ274_09680)	hexB	1950406..1952376 (+)	1971	WP_353726867.1	DNA mismatch repair endonuclease MutL	Machinery gene
ABQ274_RS09685 (ABQ274_09685)	ruvA	1952489..1953082 (+)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
ABQ274_RS09690 (ABQ274_09690)	ruvB	1953208..1954209 (+)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94318.28 Da
• Isoelectric Point: 4.6787

>NTDB_id=911185 ABQ274_RS09670 WP_353726866.1 1946945..1949467(+) (hexA) [Lactococcus lactis strain FNZ339]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQLEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLISNSAIQKRMEIVQIFLDHFFER
SDLIETLKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKYILGMLNEAPLEELKSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKTIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEKIKRQNVDNMTSREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=911185 ABQ274_RS09670 WP_353726866.1 1946945..1949467(+) (hexA) [Lactococcus lactis strain FNZ339]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCTCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTG
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAACTTGAAATTCCTGAAAATTTACTGATAGATTTGTCAGGATTGACCGCCTTAG
AAAATCAAGTCGCTTCAAAATTGTTGGCTTATGTCAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGATTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAACCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAATATATTTTAGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGCAAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTACGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGGAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGGCCTTCGGACTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGATTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAACAAGGATATATACGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCAGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACCTTGGAGCAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGGCCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTTCAAG
AGAGGCATTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (7-116)

• MutS domain II (MutS_II) (124-237)

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain V (MutS_V) (598-784)

• MutS domain III (MutS_III) (254-544)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.573	100	0.649
mutS	Pseudomonas stutzeri strain ATCC 17587	37.806	100	0.386