Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SM121_RS09340 Genome accession   NZ_CP139418
Coordinates   1897918..1899777 (-) Length   619 a.a.
NCBI ID   WP_155127841.1    Uniprot ID   A0A6A8V7P3
Organism   Streptococcus dentalis strain S1     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1892918..1904777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM121_RS09320 (SM121_09320) - 1893060..1893692 (-) 633 WP_155127850.1 response regulator transcription factor -
  SM121_RS09325 (SM121_09325) - 1893689..1894705 (-) 1017 WP_151379196.1 sensor histidine kinase -
  SM121_RS09330 (SM121_09330) liaF 1894702..1895397 (-) 696 WP_155173215.1 cell wall-active antibiotics response protein LiaF -
  SM121_RS09335 (SM121_09335) - 1895573..1897411 (-) 1839 WP_320910895.1 CAP domain-containing protein -
  SM121_RS09340 (SM121_09340) stkP 1897918..1899777 (-) 1860 WP_155127841.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SM121_RS09345 (SM121_09345) - 1899774..1900514 (-) 741 WP_003012553.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SM121_RS09350 (SM121_09350) rsmB 1900536..1901849 (-) 1314 WP_155127835.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SM121_RS09355 (SM121_09355) fmt 1901839..1902774 (-) 936 WP_155173209.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 619 a.a.        Molecular weight: 68345.50 Da        Isoelectric Point: 5.8366

>NTDB_id=909511 SM121_RS09340 WP_155127841.1 1897918..1899777(-) (stkP) [Streptococcus dentalis strain S1]
MIQIGKIFAGRYKIIQQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMAELDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTRGIIHRDLKPQNVLLTPDGTAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIREENKNVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSCLSYERRNEKKLVFEDQAKADTKTLPKVSPTPKTAPVPISEVRSEISSV
DPNRPLSDQQTMTPSKKPRRRLRARYKVLFVAIALVLTAFTFLLYMSPANKTVPDVSGKTIAEARAVIEGQDLQVGEEKE
EYSDSVAEGYVIRTNPNAGAQKKEQSRIDLIVSKGPNSFEMPNYVGETRATAEEDLKNTYKVSSKMITIEEVETFDYAAG
TVLEQTPASGEQYSLNSKTKIVLKVAKETTSIEMPNYVGSTYDFARSNLIEIYGIKEANIELRKTEHLPDGVFVSAGQIV
SQTPEVSSTVDINRTRIVLTVYEPKVTASSSTKASSSSETSSSSSAERSDTESSSSSEQ

Nucleotide


Download         Length: 1860 bp        

>NTDB_id=909511 SM121_RS09340 WP_155127841.1 1897918..1899777(-) (stkP) [Streptococcus dentalis strain S1]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCCAACAAATTGGACGCGGCGGGATGGCAGATGTTTA
TCTTGCGCGTGATTTGATTTTAGATGGGGAAGAAGTTGCAGTCAAGGTACTGCGTACGAATTACCAGACGGATCCCATTG
CAGTTGCGCGTTTTCAGCGTGAAGCAAAGGCGATGGCAGAGCTGGACCATCCAAATATCGTTCGGATTACAGACATTGGC
GAAGAAGAAGGACAACAATACCTTGCAATGGAATATGTTGCAGGTTTAGACTTGAAACGCTATATCAAAGAAAATGCTCC
TTTATCAAATGAAGAAGCTGTTCGTTTGATGGGGCAGATCCTTCTAGCTATGCGTCTTGCCCATACGCGTGGCATTATCC
ATAGAGATTTAAAACCACAGAATGTCCTCTTGACACCAGATGGAACAGCAAAAGTTTCAGACTTTGGGATTGCAGTGGCC
TTCGCAGAGACTAGCTTGACCCAGACCAACTCGATGTTGGGGTCGGTTCATTATTTGTCCCCTGAGCAGGCGCGTGGTTC
AAAAGCTACGGTGCAAAGTGACATCTACGCTATGGGGATCATTTTCTATGAGATGTTGACAGGACACATTCCTTATGATG
GAGATAGTGCAGTCACAATTGCTTTGCAGCATTTTCAAAAGCCACTCCCATCTATTCGTGAAGAAAATAAGAATGTTCCA
CAAGCTTTAGAAAATGTGGTGATCAAAGCGACAGCTAAAAAACTGACGGATCGCTATAAATCAGTGGCAGAGATGTATGT
GGATCTTTCAAGTTGCTTGTCCTATGAGAGAAGAAATGAGAAAAAACTGGTTTTTGAAGACCAAGCGAAAGCTGATACAA
AGACTCTTCCAAAAGTGAGTCCAACTCCAAAGACAGCTCCTGTTCCAATCTCTGAGGTACGCAGTGAAATCAGTTCAGTA
GATCCTAATCGACCATTATCTGATCAGCAGACAATGACGCCAAGTAAAAAGCCAAGAAGACGCTTGCGAGCGAGATACAA
GGTCTTGTTTGTTGCCATTGCCCTAGTTCTTACAGCCTTTACTTTCTTGTTGTATATGAGCCCAGCCAATAAAACCGTTC
CAGATGTTTCCGGCAAAACCATTGCCGAAGCTAGAGCGGTTATTGAGGGACAAGACCTTCAAGTTGGTGAAGAGAAAGAA
GAGTACAGTGATTCGGTGGCAGAAGGTTACGTCATTCGAACCAATCCAAATGCAGGGGCCCAAAAGAAAGAACAAAGTCG
AATTGATTTGATTGTTTCAAAAGGGCCAAACAGCTTTGAAATGCCAAATTACGTGGGTGAAACACGGGCAACAGCAGAAG
AAGATCTGAAAAATACTTATAAGGTATCAAGCAAAATGATCACGATTGAAGAAGTTGAGACCTTCGATTATGCTGCAGGG
ACAGTTCTTGAACAAACCCCAGCTTCAGGAGAGCAATATTCTCTGAATTCAAAAACCAAGATTGTTTTGAAAGTAGCGAA
AGAAACGACTTCAATTGAAATGCCAAACTATGTTGGATCAACTTATGATTTTGCTAGAAGTAATTTGATTGAGATCTATG
GTATTAAAGAAGCCAATATCGAATTAAGAAAAACGGAACATCTCCCTGATGGGGTATTTGTTTCTGCAGGTCAAATTGTC
AGCCAAACTCCAGAAGTCTCGAGTACGGTGGATATTAACCGAACACGAATTGTTTTAACGGTATATGAGCCTAAAGTGAC
GGCTTCTTCAAGCACGAAAGCCTCTTCAAGTTCAGAGACATCTAGTTCGTCCTCTGCGGAACGATCCGATACAGAAAGTT
CTAGCAGTAGTGAGCAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-245)

PASTA domain (PASTA)

(512-582)

PASTA domain (PASTA)

(440-507)

PASTA domain (PASTA)

(372-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6A8V7P3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

61.937

96.769

0.599
  stkP Streptococcus pneumoniae D39

61.77

96.769

0.598
  stkP Streptococcus pneumoniae R6

61.77

96.769

0.598
  stkP Streptococcus pneumoniae Rx1

61.603

96.769

0.596
  stkP/pknB Streptococcus salivarius strain HSISS4

54.344

94.83

0.515
  pknB Streptococcus mutans UA159

58.564

87.722

0.514