Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SM121_RS07925 Genome accession   NZ_CP139418
Coordinates   1615391..1616752 (-) Length   453 a.a.
NCBI ID   WP_320910802.1    Uniprot ID   -
Organism   Streptococcus dentalis strain S1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1610391..1621752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM121_RS07905 (SM121_07905) - 1611383..1612363 (+) 981 WP_270298580.1 Gfo/Idh/MocA family protein -
  SM121_RS07910 (SM121_07910) - 1612360..1613445 (+) 1086 WP_320910800.1 DEAD/DEAH box helicase -
  SM121_RS07915 (SM121_07915) - 1613488..1614870 (-) 1383 WP_320910801.1 polysaccharide deacetylase family protein -
  SM121_RS07920 (SM121_07920) - 1614981..1615361 (-) 381 WP_003006623.1 VOC family protein -
  SM121_RS07925 (SM121_07925) ciaH 1615391..1616752 (-) 1362 WP_320910802.1 HAMP domain-containing sensor histidine kinase Regulator
  SM121_RS07930 (SM121_07930) ciaR 1616736..1617416 (-) 681 WP_037607818.1 response regulator transcription factor Regulator
  SM121_RS07935 (SM121_07935) - 1617674..1618090 (-) 417 WP_320910803.1 hypothetical protein -
  SM121_RS07940 (SM121_07940) - 1618296..1618829 (+) 534 WP_320910804.1 biotin transporter BioY -
  SM121_RS07945 (SM121_07945) - 1618886..1621429 (-) 2544 WP_320910805.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 52080.49 Da        Isoelectric Point: 6.5330

>NTDB_id=909495 SM121_RS07925 WP_320910802.1 1615391..1616752(-) (ciaH) [Streptococcus dentalis strain S1]
MLTRIKKTVGEDDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTTVDENLKTLSQDPYSLVAIAYRDQRQSNNKVENND
HEMMIPDHDKSEPKGDVTSNTTVVLLNKKYENLTTGNGFLNFKTVTFGRKLLNKVSQLQITNSYGKKESYRAYMAELNLS
DDEDDSDIKYAVVMTNISQLEQTSEEHESQIALVMICFWGISLFASLFLARLSVKPLLESMQKQKAFVENASHELRTPLA
VLQNRLETLFRKPEATIMESSENIASSLDEVRNMKLLTTNLLNIARRDDGLKPEMEDIEPSFFDQTFSNFEIIAEENDKI
FRGNNQVDKVICSDRTLLKQLMTILYDNALKYTDEDGEIQFEVQLKDKNLLLRVLDNGPGIRDEDKKRIFDRFYRVDKAR
TRQKGGFGLGLSLAKQIVEAFKGTIQVKDNKPKGTIFEVKLSIKTESRKKNRS

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=909495 SM121_RS07925 WP_320910802.1 1615391..1616752(-) (ciaH) [Streptococcus dentalis strain S1]
ATGCTAACCAGAATTAAGAAAACCGTTGGGGAAGATGATTTTTCCTACTTCATCCGATATTTTGGACTCTTTACTTTGAT
ATTCTCGGCCATGACCTTGATTATCATTCAAGTCATGCGCTCGAGTCTCTATACAACTGTCGATGAAAACCTCAAGACTC
TCAGTCAGGATCCATACTCACTTGTAGCGATTGCTTATCGAGACCAGCGACAATCGAATAATAAAGTAGAAAATAACGAT
CATGAGATGATGATCCCAGATCATGATAAATCAGAACCTAAAGGGGATGTCACATCGAATACCACTGTTGTTTTGCTCAA
TAAAAAATATGAAAACTTGACAACCGGTAATGGTTTTTTAAACTTCAAAACCGTGACATTTGGTCGGAAGCTCCTCAACA
AGGTTTCCCAGCTACAAATTACAAATAGCTATGGGAAAAAAGAAAGTTATCGGGCCTACATGGCAGAGTTGAATTTATCT
GATGATGAAGATGATAGTGATATCAAGTATGCGGTTGTCATGACCAATATCAGTCAGCTAGAGCAGACCAGTGAAGAGCA
CGAAAGTCAAATCGCCCTTGTCATGATCTGCTTCTGGGGAATCTCCTTATTCGCTAGTCTCTTCCTAGCACGTCTCAGCG
TCAAGCCCCTTCTTGAGAGTATGCAAAAGCAAAAGGCTTTCGTGGAAAATGCTTCCCATGAGTTGCGGACGCCTTTAGCA
GTTCTGCAAAATCGCCTCGAAACGCTTTTTAGGAAGCCTGAAGCGACCATTATGGAATCGAGTGAGAATATTGCATCCAG
CTTGGATGAAGTTCGAAATATGAAGCTCTTGACCACCAACCTTCTTAACATTGCCCGAAGAGATGACGGCTTGAAGCCGG
AGATGGAAGATATCGAACCAAGCTTTTTTGATCAGACCTTCTCGAATTTTGAGATCATTGCGGAAGAAAATGACAAAATT
TTCCGAGGAAACAATCAGGTGGACAAAGTCATTTGTTCTGATAGAACGCTCCTCAAGCAATTGATGACCATTCTCTATGA
CAATGCCTTGAAATATACCGATGAAGATGGCGAGATCCAATTCGAAGTTCAATTGAAGGATAAAAATCTTCTTTTGAGAG
TACTGGATAATGGTCCAGGGATTCGAGATGAGGATAAGAAACGGATTTTTGATCGTTTTTACCGGGTCGACAAGGCCAGA
ACCCGTCAGAAAGGTGGTTTTGGTTTGGGGTTATCCCTCGCTAAGCAGATTGTAGAAGCTTTCAAAGGGACCATTCAAGT
CAAAGATAATAAACCAAAAGGGACCATCTTTGAAGTGAAATTATCCATTAAGACGGAAAGTCGTAAAAAAAATCGTTCAT
AA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(225-290)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(334-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.667

99.338

0.603
  ciaH Streptococcus pneumoniae D39

60.667

99.338

0.603
  ciaH Streptococcus pneumoniae R6

60.667

99.338

0.603
  ciaH Streptococcus pneumoniae TIGR4

60.667

99.338

0.603
  ciaH Streptococcus mutans UA159

50.676

98.013

0.497