Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABR757_RS15555 Genome accession   NZ_CP158311
Coordinates   3214777..3215433 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CS5L     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3209777..3220433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABR757_RS15525 (ABR757_15515) yecA 3211028..3211693 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ABR757_RS15545 (ABR757_15535) pgsA 3212343..3212891 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABR757_RS15550 (ABR757_15540) uvrC 3212948..3214780 (-) 1833 WP_001283415.1 excinuclease ABC subunit UvrC Machinery gene
  ABR757_RS15555 (ABR757_15545) letA 3214777..3215433 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABR757_RS15560 (ABR757_15550) - 3215575..3215646 (+) 72 Protein_3046 transcriptional regulator -
  ABR757_RS15565 (ABR757_15555) yecU 3215729..3215905 (+) 177 WP_000590347.1 protein YecU -
  ABR757_RS15570 (ABR757_15560) yecF 3215892..3216116 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABR757_RS15575 (ABR757_15565) sdiA 3216183..3216905 (-) 723 WP_001154279.1 transcriptional regulator SdiA -
  ABR757_RS15580 (ABR757_15570) tcyN 3217135..3217887 (-) 753 WP_001273007.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABR757_RS15585 (ABR757_15575) tcyL 3217884..3218552 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ABR757_RS15590 (ABR757_15580) dcyD 3218567..3219553 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=908310 ABR757_RS15555 WP_000611335.1 3214777..3215433(-) (letA) [Escherichia coli strain CS5L]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=908310 ABR757_RS15555 WP_000611335.1 3214777..3215433(-) (letA) [Escherichia coli strain CS5L]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486