Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABRP50_RS09790 Genome accession   NZ_CP158112
Coordinates   2015622..2016278 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC187792     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2010622..2021278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABRP50_RS09755 (ABRP50_09750) dcyD 2011502..2012488 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ABRP50_RS09760 (ABRP50_09755) tcyL 2012503..2013171 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ABRP50_RS09765 (ABRP50_09760) tcyN 2013168..2013920 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABRP50_RS09770 (ABRP50_09765) sdiA 2014150..2014872 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  ABRP50_RS09775 (ABRP50_09770) yecF 2014939..2015163 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABRP50_RS09780 (ABRP50_09775) yecU 2015150..2015326 (-) 177 WP_000590347.1 protein YecU -
  ABRP50_RS09785 (ABRP50_09780) - 2015409..2015480 (-) 72 Protein_1910 transcriptional regulator -
  ABRP50_RS09790 (ABRP50_09785) letA 2015622..2016278 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABRP50_RS09795 (ABRP50_09790) uvrC 2016275..2018107 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ABRP50_RS09800 (ABRP50_09795) pgsA 2018164..2018712 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABRP50_RS09820 (ABRP50_09815) - 2019408..2020148 (-) 741 Protein_1914 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=907376 ABRP50_RS09790 WP_000611335.1 2015622..2016278(+) (letA) [Escherichia coli strain EC187792]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=907376 ABRP50_RS09790 WP_000611335.1 2015622..2016278(+) (letA) [Escherichia coli strain EC187792]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486