Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ABLU28_RS00510 Genome accession   NZ_CP157495
Coordinates   95437..96879 (+) Length   480 a.a.
NCBI ID   WP_012897229.1    Uniprot ID   -
Organism   Lactococcus lactis strain 2B-1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 90437..101879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABLU28_RS00475 (ABLU28_00475) - 90641..90832 (+) 192 WP_003131566.1 hypothetical protein -
  ABLU28_RS00480 (ABLU28_00480) rsmI 90909..91784 (-) 876 WP_058212447.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  ABLU28_RS00485 (ABLU28_00485) yabA 91784..92110 (-) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  ABLU28_RS00490 (ABLU28_00490) yaaT 92103..92885 (-) 783 WP_010905316.1 stage 0 sporulation family protein Regulator
  ABLU28_RS00495 (ABLU28_00495) - 92937..93797 (-) 861 WP_058212446.1 DNA polymerase III subunit delta' -
  ABLU28_RS00500 (ABLU28_00500) tmk 93930..94565 (-) 636 WP_012897230.1 dTMP kinase -
  ABLU28_RS00505 (ABLU28_00505) yycF 94743..95444 (+) 702 WP_003131580.1 response regulator YycF -
  ABLU28_RS00510 (ABLU28_00510) vicK 95437..96879 (+) 1443 WP_012897229.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ABLU28_RS00515 (ABLU28_00515) vicX 97047..97859 (+) 813 WP_311875190.1 MBL fold metallo-hydrolase Regulator
  ABLU28_RS00520 (ABLU28_00520) groL 97905..99533 (-) 1629 WP_003131585.1 chaperonin GroEL -
  ABLU28_RS00525 (ABLU28_00525) groES 99621..99905 (-) 285 WP_003131589.1 co-chaperone GroES -
  ABLU28_RS00530 (ABLU28_00530) ssbB 100025..100414 (-) 390 WP_406835312.1 single-stranded DNA-binding protein Machinery gene
  ABLU28_RS00535 (ABLU28_00535) nox 100504..101844 (-) 1341 WP_406835310.1 H2O-forming NADH oxidase -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54649.12 Da        Isoelectric Point: 4.5889

>NTDB_id=905845 ABLU28_RS00510 WP_012897229.1 95437..96879(+) (vicK) [Lactococcus lactis strain 2B-1]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=905845 ABLU28_RS00510 WP_012897229.1 95437..96879(+) (vicK) [Lactococcus lactis strain 2B-1]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACACGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACTTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGACGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGACAATGCTTCAAGAAATTCAAAAGTTGGGGGAACAGGTTTAGGCCTCTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACAACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGTACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442