Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SHN03_RS09660 Genome accession   NZ_CP138566
Coordinates   1984950..1985579 (-) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain AUSMDU00020487     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1979950..1990579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SHN03_RS09635 - 1980917..1981117 (-) 201 WP_001813025.1 DUF1128 family protein -
  SHN03_RS09640 - 1981264..1981728 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  SHN03_RS09645 - 1981735..1982010 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  SHN03_RS09650 - 1982298..1983470 (-) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  SHN03_RS09655 - 1983620..1984837 (+) 1218 WP_000037083.1 YihY/virulence factor BrkB family protein -
  SHN03_RS09660 vraR 1984950..1985579 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  SHN03_RS09665 vraS 1985569..1986612 (-) 1044 WP_001017129.1 sensor histidine kinase Regulator
  SHN03_RS09670 liaF 1986609..1987310 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  SHN03_RS09675 - 1987325..1987711 (-) 387 WP_001110183.1 hypothetical protein -
  SHN03_RS09680 map 1987928..1988686 (-) 759 WP_000636137.1 type I methionyl aminopeptidase -
  SHN03_RS09685 - 1989329..1990315 (+) 987 WP_000999711.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=903496 SHN03_RS09660 WP_000153535.1 1984950..1985579(-) (vraR) [Staphylococcus aureus strain AUSMDU00020487]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=903496 SHN03_RS09660 WP_000153535.1 1984950..1985579(-) (vraR) [Staphylococcus aureus strain AUSMDU00020487]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCACATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGTGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373