Detailed information NTG0902425

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SE861_RS00410
• Genome accession: NZ_CP138371
• Coordinates: 64140..65042 (+)
• Length: 300 a.a.
• NCBI ID: WP_000912098.1
• Uniprot ID: A0AAD2WWZ7
• Organism: Streptococcus agalactiae strain R31-snf2
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 59140..70042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE861_RS00385 (SE861_00385)	purE	59316..59807 (+)	492	WP_001875905.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SE861_RS00390 (SE861_00390)	purK	59794..60867 (+)	1074	WP_001048172.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SE861_RS00395 (SE861_00395)	-	60877..61134 (+)	258	WP_000590468.1	hypothetical protein	-
SE861_RS00400 (SE861_00400)	-	61500..62603 (+)	1104	WP_001867169.1	DUF6287 domain-containing protein	-
SE861_RS00405 (SE861_00405)	purB	62689..63987 (+)	1299	WP_000893937.1	adenylosuccinate lyase	-
SE861_RS00410 (SE861_00410)	comR	64140..65042 (+)	903	WP_000912098.1	helix-turn-helix domain-containing protein	Regulator
SE861_RS00415 (SE861_00415)	ruvB	65331..66329 (+)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	-
SE861_RS00420 (SE861_00420)	-	66481..66918 (+)	438	WP_000754817.1	low molecular weight protein-tyrosine-phosphatase	-
SE861_RS00425 (SE861_00425)	-	66925..67305 (+)	381	WP_000787702.1	membrane protein	-
SE861_RS00430 (SE861_00430)	-	67302..69080 (+)	1779	WP_001220911.1	acyltransferase family protein	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35606.08 Da
• Isoelectric Point: 6.5030

>NTDB_id=902425 SE861_RS00410 WP_000912098.1 64140..65042(+) (comR) [Streptococcus agalactiae strain R31-snf2]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide

• Length: 903 bp

>NTDB_id=902425 SE861_RS00410 WP_000912098.1 64140..65042(+) (comR) [Streptococcus agalactiae strain R31-snf2]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-295)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	59.375	96	0.57
comR	Streptococcus mutans UA159	52.174	99.667	0.52
comR	Streptococcus pyogenes MGAS8232	50.166	100	0.503
comR	Streptococcus pyogenes MGAS315	47.667	100	0.477
comR	Streptococcus suis P1/7	40.067	99	0.397
comR	Streptococcus suis 05ZYH33	40.067	99	0.397
comR	Streptococcus suis D9	36.184	100	0.367