Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABH608_RS09080 Genome accession   NZ_CP157088
Coordinates   1888395..1889051 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli isolate FELIX_MS490     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1883395..1894051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABH608_RS09045 (ABH608_09040) dcyD 1884274..1885260 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ABH608_RS09050 (ABH608_09045) tcyL 1885275..1885943 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ABH608_RS09055 (ABH608_09050) tcyN 1885940..1886692 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABH608_RS09060 (ABH608_09055) sdiA 1886922..1887644 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  ABH608_RS09065 (ABH608_09060) yecF 1887712..1887936 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABH608_RS09070 (ABH608_09065) yecU 1887923..1888099 (-) 177 WP_000590347.1 protein YecU -
  ABH608_RS09075 (ABH608_09070) - 1888182..1888253 (-) 72 Protein_1769 transcriptional regulator -
  ABH608_RS09080 (ABH608_09075) letA 1888395..1889051 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABH608_RS09085 (ABH608_09080) uvrC 1889048..1890880 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ABH608_RS09090 (ABH608_09085) pgsA 1890937..1891485 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABH608_RS09110 (ABH608_09105) yecA 1892135..1892800 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=901740 ABH608_RS09080 WP_000611335.1 1888395..1889051(+) (letA) [Escherichia coli isolate FELIX_MS490]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=901740 ABH608_RS09080 WP_000611335.1 1888395..1889051(+) (letA) [Escherichia coli isolate FELIX_MS490]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486