Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGD   Type   Machinery gene
Locus tag   SC043_RS10965 Genome accession   NZ_CP138309
Coordinates   2158002..2158418 (-) Length   138 a.a.
NCBI ID   WP_021216554.1    Uniprot ID   A0AAC9R430
Organism   Lactococcus lactis strain B26     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2154731..2194279 2158002..2158418 within 0


Gene organization within MGE regions


Location: 2154731..2194279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SC043_RS10935 (SC043_10935) - 2154731..2155468 (-) 738 WP_010906311.1 metal ABC transporter ATP-binding protein -
  SC043_RS10940 (SC043_10940) - 2155645..2156487 (-) 843 WP_010906312.1 metal ABC transporter substrate-binding protein -
  SC043_RS10945 (SC043_10945) - 2156484..2156921 (-) 438 WP_010906313.1 zinc-dependent MarR family transcriptional regulator -
  SC043_RS10950 (SC043_10950) comGG 2157002..2157286 (-) 285 WP_010906314.1 competence type IV pilus minor pilin ComGG Machinery gene
  SC043_RS10955 (SC043_10955) comGF 2157325..2157771 (-) 447 WP_031296844.1 competence type IV pilus minor pilin ComGF Machinery gene
  SC043_RS10960 (SC043_10960) comGE 2157734..2158030 (-) 297 WP_010906316.1 competence type IV pilus minor pilin ComGE Machinery gene
  SC043_RS10965 (SC043_10965) comGD 2158002..2158418 (-) 417 WP_021216554.1 competence type IV pilus minor pilin ComGD Machinery gene
  SC043_RS10970 (SC043_10970) comGC 2158393..2158677 (-) 285 WP_032941550.1 competence type IV pilus major pilin ComGC Machinery gene
  SC043_RS10975 (SC043_10975) - 2158809..2159333 (-) 525 WP_014570795.1 GNAT family N-acetyltransferase -
  SC043_RS10980 (SC043_10980) - 2159412..2160191 (-) 780 WP_058147788.1 peptidoglycan amidohydrolase family protein -
  SC043_RS10985 (SC043_10985) - 2160191..2160490 (-) 300 WP_031559226.1 phage holin -
  SC043_RS10990 (SC043_10990) - 2160503..2160853 (-) 351 WP_023349296.1 hypothetical protein -
  SC043_RS13085 - 2160873..2161718 (-) 846 Protein_2141 hypothetical protein -
  SC043_RS11000 (SC043_11000) - 2162431..2162604 (-) 174 WP_032941620.1 hypothetical protein -
  SC043_RS11005 (SC043_11005) - 2162604..2163725 (-) 1122 WP_031297171.1 hypothetical protein -
  SC043_RS11010 (SC043_11010) - 2163742..2165535 (-) 1794 WP_031297170.1 phage tail protein -
  SC043_RS11015 (SC043_11015) - 2165532..2167052 (-) 1521 WP_058147722.1 distal tail protein Dit -
  SC043_RS11020 (SC043_11020) - 2167062..2169671 (-) 2610 WP_023349195.1 hypothetical protein -
  SC043_RS11025 (SC043_11025) - 2169661..2170368 (-) 708 WP_014570560.1 Gp15 family bacteriophage protein -
  SC043_RS11030 (SC043_11030) - 2170384..2170791 (-) 408 WP_003131323.1 hypothetical protein -
  SC043_RS11035 (SC043_11035) - 2170848..2171324 (-) 477 WP_014570559.1 phage tail tube protein -
  SC043_RS11040 (SC043_11040) - 2171335..2171769 (-) 435 WP_003131321.1 minor capsid protein -
  SC043_RS11045 (SC043_11045) - 2171769..2172098 (-) 330 WP_003131320.1 hypothetical protein -
  SC043_RS11050 (SC043_11050) - 2172095..2172439 (-) 345 WP_003131319.1 putative minor capsid protein -
  SC043_RS11055 (SC043_11055) - 2172429..2172830 (-) 402 WP_014570556.1 hypothetical protein -
  SC043_RS11060 (SC043_11060) - 2172904..2173140 (-) 237 WP_023349196.1 Ig-like domain-containing protein -
  SC043_RS11065 (SC043_11065) - 2173169..2174086 (-) 918 WP_023349197.1 phage capsid protein -
  SC043_RS11070 (SC043_11070) - 2174101..2175153 (-) 1053 WP_023349198.1 XkdF-like putative serine protease domain-containing protein -
  SC043_RS11075 (SC043_11075) - 2175169..2175999 (-) 831 WP_023349199.1 phage minor head protein -
  SC043_RS11080 (SC043_11080) - 2175992..2177521 (-) 1530 WP_023349200.1 phage portal protein -
  SC043_RS11085 (SC043_11085) terL 2177534..2178985 (-) 1452 WP_023349201.1 phage terminase large subunit -
  SC043_RS11090 (SC043_11090) - 2178966..2179463 (-) 498 WP_023349202.1 hypothetical protein -
  SC043_RS11095 (SC043_11095) - 2179492..2180649 (-) 1158 WP_023349203.1 DNA modification methylase -
  SC043_RS11105 (SC043_11105) - 2181126..2181548 (-) 423 WP_023349204.1 RinA family protein -
  SC043_RS11110 (SC043_11110) - 2181625..2181933 (-) 309 WP_023349205.1 hypothetical protein -
  SC043_RS11115 (SC043_11115) - 2182062..2182256 (-) 195 WP_023349206.1 DUF1660 domain-containing protein -
  SC043_RS11120 (SC043_11120) - 2182253..2182471 (-) 219 WP_014570803.1 hypothetical protein -
  SC043_RS11125 (SC043_11125) - 2182518..2182763 (-) 246 WP_023349207.1 hypothetical protein -
  SC043_RS11130 (SC043_11130) - 2182785..2183144 (-) 360 WP_023349208.1 hypothetical protein -
  SC043_RS11135 (SC043_11135) dut 2183147..2183566 (-) 420 WP_023349209.1 dUTP diphosphatase -
  SC043_RS11140 (SC043_11140) - 2183563..2183868 (-) 306 WP_023349170.1 hypothetical protein -
  SC043_RS11145 (SC043_11145) - 2183865..2184368 (-) 504 WP_023349171.1 DUF1642 domain-containing protein -
  SC043_RS11150 (SC043_11150) - 2184361..2184567 (-) 207 WP_010905356.1 DUF1125 domain-containing protein -
  SC043_RS11155 (SC043_11155) - 2185073..2185483 (-) 411 WP_014570810.1 hypothetical protein -
  SC043_RS11160 (SC043_11160) - 2185496..2185738 (-) 243 WP_023349173.1 L-rhamnose isomerase -
  SC043_RS11165 (SC043_11165) - 2185731..2186654 (-) 924 WP_023349174.1 phage replisome organizer N-terminal domain-containing protein -
  SC043_RS11170 (SC043_11170) - 2186918..2187844 (-) 927 WP_014570813.1 RecT family recombinase -
  SC043_RS11175 (SC043_11175) - 2187841..2188674 (-) 834 WP_023349175.1 hypothetical protein -
  SC043_RS11180 (SC043_11180) - 2188777..2189025 (-) 249 WP_014570815.1 hypothetical protein -
  SC043_RS11185 (SC043_11185) - 2189039..2189161 (-) 123 WP_023164646.1 hypothetical protein -
  SC043_RS11190 (SC043_11190) - 2189158..2189340 (-) 183 WP_023349176.1 hypothetical protein -
  SC043_RS11195 (SC043_11195) - 2189404..2189613 (-) 210 WP_023349177.1 helix-turn-helix transcriptional regulator -
  SC043_RS11200 (SC043_11200) - 2189804..2190226 (+) 423 WP_023349178.1 helix-turn-helix transcriptional regulator -
  SC043_RS11205 (SC043_11205) - 2190237..2190821 (+) 585 WP_023349179.1 hypothetical protein -
  SC043_RS11210 (SC043_11210) - 2190875..2191537 (+) 663 WP_023349180.1 SHOCT domain-containing protein -
  SC043_RS11215 (SC043_11215) - 2191652..2193109 (+) 1458 WP_023349181.1 recombinase family protein -
  SC043_RS11220 (SC043_11220) - 2193106..2193246 (-) 141 WP_023349182.1 hypothetical protein -

Sequence


Protein


Download         Length: 138 a.a.        Molecular weight: 15902.69 Da        Isoelectric Point: 7.9826

>NTDB_id=901726 SC043_RS10965 WP_021216554.1 2158002..2158418(-) (comGD) [Lactococcus lactis strain B26]
MKNEILMTKAFTLLESLLVLLIISFITTLFSLEIIQTIHLFKGELFVLQFENFYKRSQEDAALLQKSESLVAKNQELICE
DRSITIPKEVAVKDFTVKFDDKGENSSLQKLTISLPYEKKFITYQLEIGSGKFKKKIS

Nucleotide


Download         Length: 417 bp        

>NTDB_id=901726 SC043_RS10965 WP_021216554.1 2158002..2158418(-) (comGD) [Lactococcus lactis strain B26]
ATGAAGAACGAAATTTTAATGACTAAAGCATTTACTTTACTAGAGTCTCTTCTAGTTTTGTTGATTATTTCTTTTATCAC
AACTCTTTTTTCTTTAGAAATAATACAAACAATCCATCTTTTTAAGGGAGAATTGTTTGTTCTTCAATTTGAAAATTTCT
ATAAAAGGAGTCAAGAAGATGCTGCACTGCTTCAAAAATCTGAAAGTTTAGTTGCTAAAAATCAAGAATTAATCTGTGAA
GATAGAAGTATCACAATTCCAAAGGAGGTAGCAGTTAAAGATTTTACAGTTAAATTTGATGATAAGGGAGAGAATTCTAG
CTTACAAAAACTCACAATTTCTTTACCTTACGAAAAAAAGTTCATCACTTATCAATTGGAGATAGGCAGTGGAAAATTTA
AAAAGAAAATCAGTTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Lactococcus lactis subsp. cremoris KW2

65.942

100

0.659

  comYD Streptococcus gordonii str. Challis substr. CH1

40.458

94.928

0.384

  comYD Streptococcus mutans UA140

40.625

92.754

0.377

  comYD Streptococcus mutans UA159

40.625

92.754

0.377