Detailed information NTG0897380

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ABC806_RS01445
• Genome accession: NZ_CP155539
• Coordinates: 270042..270941 (+)
• Length: 299 a.a.
• NCBI ID: WP_000904858.1
• Uniprot ID: A0A0H2URY1
• Organism: Streptococcus pneumoniae TIGR4
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 265042..275941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC806_RS01415 (ABC806_01415)	-	265212..265506 (+)	295	Protein_249	hypothetical protein	-
ABC806_RS01420 (ABC806_01420)	-	265662..266876 (+)	1215	WP_000666479.1	pyridoxal phosphate-dependent aminotransferase	-
ABC806_RS01425 (ABC806_01425)	rpmH	267021..267155 (+)	135	WP_000831905.1	50S ribosomal protein L34	-
ABC806_RS01430 (ABC806_01430)	-	267439..268332 (+)	894	WP_000226469.1	cell wall surface anchor protein	-
ABC806_RS01435 (ABC806_01435)	-	268637..269410 (+)	774	WP_000575607.1	TatD family hydrolase	-
ABC806_RS01440 (ABC806_01440)	rnmV	269410..269970 (+)	561	WP_000660004.1	ribonuclease M5	-
ABC806_RS01445 (ABC806_01445)	comR	270042..270941 (+)	900	WP_000904858.1	helix-turn-helix transcriptional regulator	Regulator
ABC806_RS01450 (ABC806_01450)	-	271210..273240 (+)	2031	WP_000825267.1	bacteriocin-associated integral membrane family protein	-
ABC806_RS01455 (ABC806_01455)	-	273242..273883 (+)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
ABC806_RS01460 (ABC806_01460)	-	273876..274184 (+)	309	WP_000333257.1	hypothetical protein	-
ABC806_RS01465 (ABC806_01465)	rsmA	274315..275187 (+)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35409.11 Da
• Isoelectric Point: 4.7119

>NTDB_id=897380 ABC806_RS01445 WP_000904858.1 270042..270941(+) (comR) [Streptococcus pneumoniae TIGR4]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=897380 ABC806_RS01445 WP_000904858.1 270042..270941(+) (comR) [Streptococcus pneumoniae TIGR4]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

3D structure

• AlphaFold DB: A0A0H2URY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361