Detailed information NTG0896194

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R4701_RS06620
• Genome accession: NZ_CP137114
• Coordinates: 1301562..1302572 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 15P3054
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1296562..1307572

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4701_RS06590	-	1297433..1297639 (+)	207	WP_000503440.1	hypothetical protein	-
R4701_RS06595	-	1297636..1297830 (+)	195	WP_000820188.1	hypothetical protein	-
R4701_RS06600	-	1297817..1298701 (+)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
R4701_RS06605	-	1298703..1299440 (+)	738	WP_000832918.1	ABC transporter permease	-
R4701_RS06610	-	1299440..1300537 (+)	1098	WP_000893497.1	sensor histidine kinase	-
R4701_RS06615	-	1300538..1301137 (+)	600	WP_000866703.1	response regulator transcription factor	-
R4701_RS06620	ccpA	1301562..1302572 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
R4701_RS06625	-	1302636..1302839 (+)	204	WP_001092033.1	hypothetical protein	-
R4701_RS06630	-	1302868..1303830 (-)	963	WP_001124777.1	asparaginase	-
R4701_RS06635	-	1303896..1305284 (+)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
R4701_RS06640	-	1305319..1305771 (-)	453	WP_000079148.1	universal stress protein	-
R4701_RS06645	-	1305933..1306227 (+)	295	Protein_1284	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=896194 R4701_RS06620 WP_000990607.1 1301562..1302572(+) (ccpA) [Streptococcus pneumoniae strain 15P3054]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=896194 R4701_RS06620 WP_000990607.1 1301562..1302572(+) (ccpA) [Streptococcus pneumoniae strain 15P3054]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568