Detailed information NTG0896021

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R4700_RS04200
• Genome accession: NZ_CP137112
• Coordinates: 813317..814327 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 02H2025
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 808317..819327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4700_RS04175	-	809663..809956 (-)	294	WP_000977365.1	hypothetical protein	-
R4700_RS04180	-	810118..810570 (+)	453	WP_000079148.1	universal stress protein	-
R4700_RS04185	-	810605..811993 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
R4700_RS04190	-	812059..813021 (+)	963	WP_001124777.1	asparaginase	-
R4700_RS04195	-	813050..813253 (-)	204	WP_001092033.1	hypothetical protein	-
R4700_RS04200	ccpA	813317..814327 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R4700_RS04205	-	814752..815351 (-)	600	WP_000866703.1	response regulator transcription factor	-
R4700_RS04210	-	815352..816449 (-)	1098	WP_000893503.1	sensor histidine kinase	-
R4700_RS04215	-	816449..817186 (-)	738	WP_000832916.1	ABC transporter permease	-
R4700_RS04220	-	817188..818072 (-)	885	WP_061637049.1	ABC transporter ATP-binding protein	-
R4700_RS04225	-	818059..818253 (-)	195	WP_000820189.1	hypothetical protein	-
R4700_RS04230	-	818250..818456 (-)	207	WP_061637051.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=896021 R4700_RS04200 WP_000990607.1 813317..814327(-) (ccpA) [Streptococcus pneumoniae strain 02H2025]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=896021 R4700_RS04200 WP_000990607.1 813317..814327(-) (ccpA) [Streptococcus pneumoniae strain 02H2025]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568