Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   R4700_RS00650 Genome accession   NZ_CP137112
Coordinates   128777..129625 (-) Length   282 a.a.
NCBI ID   WP_317770891.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 02H2025     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 127032..127985 128777..129625 flank 792


Gene organization within MGE regions


Location: 127032..129625
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4700_RS00640 - 127032..127985 (-) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -
  R4700_RS00645 - 128471..128593 (+) 123 WP_001814242.1 hypothetical protein -
  R4700_RS00650 dprA/cilB/dalA 128777..129625 (-) 849 WP_317770891.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31019.70 Da        Isoelectric Point: 5.4047

>NTDB_id=895996 R4700_RS00650 WP_317770891.1 128777..129625(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 02H2025]
MKITNYEIYKLKKSGLTNLQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=895996 R4700_RS00650 WP_317770891.1 128777..129625(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 02H2025]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCTACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGCTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae D39

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae R6

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

99.291

100

0.993
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

97.872

100

0.979
  dprA/cilB/dalA Streptococcus mitis SK321

97.163

100

0.972
  dprA Streptococcus mutans UA159

63.571

99.291

0.631
  dprA Lactococcus lactis subsp. cremoris KW2

55.714

99.291

0.553
  dprA Haemophilus influenzae Rd KW20

38.202

94.681

0.362