Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   R4706_RS09050 Genome accession   NZ_CP137111
Coordinates   1775950..1777908 (+) Length   652 a.a.
NCBI ID   WP_000748873.1    Uniprot ID   A0A0B7M1B9
Organism   Streptococcus pneumoniae strain 17023     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770950..1782908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS09025 - 1771087..1771599 (+) 513 WP_000892251.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -
  R4706_RS09030 - 1771583..1772232 (+) 650 Protein_1735 DUF1803 domain-containing protein -
  R4706_RS09035 - 1772333..1772527 (+) 195 WP_000051201.1 CsbD family protein -
  R4706_RS09040 - 1772573..1774018 (-) 1446 WP_044727610.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  R4706_RS09045 - 1774124..1775746 (+) 1623 WP_000017793.1 polysaccharide biosynthesis protein -
  R4706_RS09050 amiA 1775950..1777908 (+) 1959 WP_000748873.1 peptide ABC transporter substrate-binding protein Regulator
  R4706_RS09055 - 1778080..1779015 (+) 936 WP_000768992.1 ABC transporter ATP-binding protein -
  R4706_RS10835 - 1779040..1779479 (+) 440 Protein_1741 ATP-binding cassette domain-containing protein -
  R4706_RS10840 - 1779609..1779761 (+) 153 WP_001812505.1 hypothetical protein -
  R4706_RS09065 - 1779919..1781013 (+) 1095 WP_000031966.1 cystathionine gamma-synthase -
  R4706_RS09070 - 1781021..1782187 (+) 1167 WP_044727612.1 MalY/PatB family protein -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72561.97 Da        Isoelectric Point: 4.9968

>NTDB_id=895986 R4706_RS09050 WP_000748873.1 1775950..1777908(+) (amiA) [Streptococcus pneumoniae strain 17023]
MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSL
AEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAK
NVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTS
DIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINF
ADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDS
SGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKR
YEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=895986 R4706_RS09050 WP_000748873.1 1775950..1777908(+) (amiA) [Streptococcus pneumoniae strain 17023]
ATGAAAAAGTCTAAGAGCAAATATCTAACCTTGGCAGGTCTTGTCCTGGGTACAGGAGTTTTATTGAGCGCGTGTGGAAA
TTCTAGCACGGCGTCAAAAACATACAACTATGTTTATTCAAGTGATCCATCTAGCTTGAACTATCTAGCAGAAAACCGCG
CAGCAACATCCGATATTGTTGCAAATTTGGTAGACGGGTTATTAGAAAATGACCAATATGGGAATATTATTCCATCATTA
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACCTACAAACTTCGTAAGGATGCCAAGTGGTTTACTTCTGA
GGGAGAAGAATATGCGCCTGTAACTGCCCAGGATTTTGTGACAGGTTTGCAATATGCAGCTGATAAAAAATCAGAAGCCT
TGTATCTAGTGCAGGACTCTGTTGCTGGTTTGGATGACTATATCACTGGTAAAACAAGCGACTTTTCAACTGTCGGTGTC
AAGGCACTTGATGACCAAACGGTTCAATATACTTTGGTTAAACCAGAACTTTACTGGAATTCAAAAACACTTGCAACGAT
ACTTTTTCCTGTTAATGCAGATTTCCTGAAATCAAAAGGGGATGATTTTGGGAAGGCGGATCCATCTAGTATTTTGTACA
ATGGACCTTTCTTGATGAAAGCACTTGTCTCAAAATCTGCTATTGAATATAAGAAAAACCCTAATTACTGGGATGCTAAG
AATGTCTTTGTAGACGATGTGAAATTGACCTACTATGATGGTAGCGACCAAGAATCACTGGAACGTAATTTTACAGCTGG
TGCTTATACTACGGCTCGTCTTTTTCCTAACAGCTCCAGCTATGAAGGGATTAAAGAAAAATACAAAAACAATATCATCT
ATAGTATGCAAAATTCAACTTCATATTTCTTTAATTTTAACCTAGATAGGAAGTCTTACAATTATACTTCTAAAACAAGT
GACATTGAAAAGAAATCGACTCAGGAAGCAGTTCTCAATAAAAACTTCCGTCAGGCTATCAATTTTGCTTTTGACAGAAC
ATCTTATGGGGCTCAGTCTGAAGGGAAAGAAGGTGCAACAAAGATTTTGCGTAACCTAGTGGTTCCTCCAAACTTTGTCA
GTATCAAGGGAAAAGACTTTGGTGAAGTTGTAGCCTCTAAGATGGTCAACTATGGTAAGGAATGGCAAGGTATCAACTTT
GCGGATGGTCAAGACCCTTACTACAATCCTGAGAAAGCCAAGGCTAAGTTTGCGGAAGCTAAGAAAGAACTCGAAGCAAA
GGGTGTTCAATTCCCAATCCACTTGGATAAGACTGTGGAAGTAACAGATAAAGTAGGCATACAAGGAGTTAGTTCTATCA
AACAATCAATTGAATCTGTTTTAGGTTCTGATAATGTAGTGATTGACATTCAGCAATTAACATCAGATGAGTTTGACAGT
TCAGGCTACTTTGCTCAAACAGCTGCTCAGAAAGACTATGATTTATATCATGGCGGTTGGGGACCTGATTATCAAGACCC
GTCAACCTATCTCGATATTTTTAATACTAATAGTGGAGGATTTCTGCAAAATCTTGGACTAGAGCCTGGTGAGGCCAATG
ACAAGGCTAAGGCAGTTGGACTGGATGTCTATACTCAAATGTTGGAAGAAGCTAATAAAGAGCAAGATCCAGCCAAACGT
TATGAGAAATATGCTGATATTCAAGCTTGGTTGATTGATAGTTCTTTAGTTCTTCCAAGTGTTTCGCGTGGGGGAACACC
ATCATTGAGAAGAACCGTACCATTTGCTGCTGCCTATGGTTTAACCGGTACAAAAGGGGTTGAATCATATAAATACCTCA
AAGTACAAGATAAGATTGTCACAACAGACGAATATGCAAAAGCCAGAGAAAAATGGTTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M1B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

56.422

100

0.566
  amiA3 Streptococcus thermophilus LMD-9

55.878

100

0.561
  amiA3 Streptococcus thermophilus LMG 18311

55.725

100

0.56