Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   R4706_RS06100 Genome accession   NZ_CP137111
Coordinates   1223907..1224614 (-) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 17023     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1225257..1225727 1223907..1224614 flank 643


Gene organization within MGE regions


Location: 1223907..1225727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS06100 vicR 1223907..1224614 (-) 708 WP_000166475.1 response regulator transcription factor Regulator
  R4706_RS06105 - 1224698..1225183 (-) 486 WP_044727788.1 cupin domain-containing protein -
  R4706_RS06110 - 1225169..1225727 (+) 559 Protein_1207 transposase family protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=895952 R4706_RS06100 WP_000166475.1 1223907..1224614(-) (vicR) [Streptococcus pneumoniae strain 17023]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=895952 R4706_RS06100 WP_000166475.1 1223907..1224614(-) (vicR) [Streptococcus pneumoniae strain 17023]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCGATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396