Detailed information NTG0895621

Bioinformatically predicted

Overview

• Name: amiA3
• Type: Regulator
• Locus tag: R4711_RS03640
• Genome accession: NZ_CP137107
• Coordinates: 731249..733231 (-)
• Length: 660 a.a.
• NCBI ID: WP_000842576.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15H4024
• Function: binding to XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	734031..747724	731249..733231	flank	800
IS/Tn	733553..733942	731249..733231	flank	322

Gene organization within MGE regions

Location: 731249..747724

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4711_RS03640	amiA3	731249..733231 (-)	1983	WP_000842576.1	peptide ABC transporter substrate-binding protein	Regulator
R4711_RS03645	-	733550..733942 (+)	393	Protein_724	transposase	-
R4711_RS03650	-	734031..734864 (-)	834	WP_000779206.1	HAD-IIA family hydrolase	-
R4711_RS03655	-	734879..735583 (-)	705	WP_000645462.1	sugar phosphate nucleotidyltransferase	-
R4711_RS03660	-	735599..736627 (-)	1029	WP_000794265.1	iron-containing alcohol dehydrogenase family protein	-
R4711_RS03665	-	736663..737811 (-)	1149	WP_000261152.1	CDP-glycerol--glycerophosphate glycerophosphotransferase	-
R4711_RS03670	-	737813..738796 (-)	984	WP_317806049.1	acyltransferase	-
R4711_RS03675	-	739162..740625 (-)	1464	WP_000066240.1	flippase	-
R4711_RS03680	-	740630..741538 (-)	909	WP_000570494.1	capsular polysaccharide synthesis protein	-
R4711_RS03685	-	741554..742510 (-)	957	WP_000389753.1	glycosyltransferase	-
R4711_RS03690	-	742518..743543 (-)	1026	WP_000573792.1	glycosyltransferase family 2 protein	-
R4711_RS03695	-	743540..744712 (-)	1173	WP_000702185.1	polysaccharide polymerase	-
R4711_RS03700	-	744702..745205 (-)	504	WP_000578430.1	glycosyltransferase	-
R4711_RS03705	pssD	745205..745654 (-)	450	WP_000861663.1	PssD/Cps14F family polysaccharide biosynthesis glycosyltransferase	-
R4711_RS03710	-	745658..747025 (-)	1368	WP_000343580.1	sugar transferase	-
R4711_RS03715	cpsD	747041..747724 (-)	684	WP_001142510.1	polysaccharide biosynthesis tyrosine autokinase CpsD	-

Sequence

Protein

• Length: 660 a.a.
• Molecular weight: 73036.67 Da
• Isoelectric Point: 4.7548

>NTDB_id=895621 R4711_RS03640 WP_000842576.1 731249..733231(-) (amiA3) [Streptococcus pneumoniae strain 15H4024]
MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPS
MAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWD
KDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSK
TSDEQKASTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDV
NLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVIIDIQQLQKDEV
NNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEAT
DVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKW
MKEKEESNKKAQEDLAKHVK

Nucleotide

• Length: 1983 bp

>NTDB_id=895621 R4711_RS03640 WP_000842576.1 731249..733231(-) (amiA3) [Streptococcus pneumoniae strain 15H4024]
ATGAAAAGTTCAAAACTATTTGCCCTTGCGGGCGTGACATTATTGGCGGCGACTACTTTAGCTGCATGCTCTGGATCAGG
TTCAAGTACTAAAGGTGAGAAGACATTCTCATACATTTATGAGACAGACCCTGATAACCTCAACTATTTGACAACTGCTA
AGGCTGCGACAGCAAATATTACCAGTAACGTGGTTGATGGTTTGCTAGAAAATGATCGCTACGGGAACTTTGTGCCGTCT
ATGGCTGAGGATTGGTCTGTATCCAAGGATGGATTGACTTACACTTATACTATCCGTAAGGATGCAAAATGGTATACTTC
TGAAGGTGAAGAATACGCGGCAGTCAAAGCTCAAGACTTTGTAACAGGACTAAAATATGCTGCTGATAAAAAATCAGATG
CTCTTTACCTTGTTCAAGAATCAATCAAAGGGTTGGATGCCTATGTAAAAGGGGAAATCAAAGATTTCTCACAAGTAGGA
ATTAAGGCTCTGGATGAACAGACAGTTCAGTACACTTTGAACAAACCAGAAAGCTTCTGGAATTCTAAGACAACCATGGG
TGTGCTTGCGCCAGTTAATGAAGAGTTTTTGAATTCAAAAGGGGATGATTTTGCCAAAGCTACGGATCCAAGTAGTCTCT
TGTATAACGGTCCTTATTTGTTGAAATCCATTGTGACCAAATCTTCTGTTGAATTTGCGAAAAATCCGAACTACTGGGAT
AAGGACAATGTGCATATTGACAAAGTTAAATTGTCATTCTGGGATGGTCAAGATACCAGCAAACCTGCAGAAAACTTTAA
AGATGGTAGCCTTACAGCAGCTCGTCTCTATCCAACAAGTGCAAGTTTCGCAGAGCTTGAGAAGAGTATGAAGGACAATA
TTGTCTATACTCAACAAGACTCTATTACGTATCTAGTTGGTACAAATATTGACCGTCAGTCCTATAAATACACATCTAAG
ACCAGCGATGAACAAAAGGCATCGACTAAAAAGGCTCTCTTAAACAAGGATTTCCGTCAGGCTATTGCCTTTGGTTTTGA
TCGTACAGCCTATGCCTCTCAGTTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATATCTTTGTTCCACCAACAT
TTGTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTCACTTATGGGGATGAATGGAAGGATGTT
AATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAAGCCAAGGCTGAATTTGCTAAAGCTAAATCAGCCTTACA
AGCAGAAGGTGTGACATTCCCAATTCATTTGGATATGCCAGTTGACCAAACAGCAACTACAAAAGTTCAGCGCGTCCAAT
CTATGAAACAATCCTTGGAAGCAACTTTAGGAGCTGATAATGTCATTATTGATATCCAACAACTACAAAAAGACGAAGTA
AACAATATTACATATTTTGCTGAAAATGCTGCTGGCGAAGACTGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTT
TGCCGATCCATCAACCTACCTTGATATCATCAAACCATCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAG
GGGAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAGGCTGGTGATGAGGCTACA
GATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCTTGGTTGACAGATAGTGCTTTGATTATTCCAACTACATC
TCGTACAGGGCGTCCAATTTTGTCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGTACAAGTG
AACCAGTCTTGTATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAAAAAGCTCAGGAAAAATGG
ATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGATCTCGCAAAACATGTGAAATAA

Domains

Predicted by InterproScan.

• Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5) (77-519)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiA3	Streptococcus thermophilus LMD-9	58.245	100	0.583
amiA3	Streptococcus thermophilus LMG 18311	57.943	100	0.58
amiA	Streptococcus salivarius strain HSISS4	57.791	100	0.579