Detailed information NTG0895522

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R4699_RS10545
• Genome accession: NZ_CP137105
• Coordinates: 2084665..2085675 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 16H2092
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2079665..2090675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4699_RS10515	-	2080536..2080742 (+)	207	Protein_2033	hypothetical protein	-
R4699_RS10520	-	2080739..2080933 (+)	195	WP_000820187.1	hypothetical protein	-
R4699_RS10525	-	2080920..2081804 (+)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
R4699_RS10530	-	2081806..2082543 (+)	738	WP_050104940.1	ABC transporter permease	-
R4699_RS10535	-	2082543..2083640 (+)	1098	WP_000893498.1	sensor histidine kinase	-
R4699_RS10540	-	2083641..2084240 (+)	600	WP_000866702.1	response regulator transcription factor	-
R4699_RS10545	ccpA	2084665..2085675 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
R4699_RS10550	-	2085739..2086110 (+)	372	WP_057529614.1	hypothetical protein	-
R4699_RS10555	-	2086107..2087069 (-)	963	WP_001124777.1	asparaginase	-
R4699_RS10560	-	2087135..2088523 (+)	1389	WP_050104942.1	Cof-type HAD-IIB family hydrolase	-
R4699_RS10565	-	2088558..2089010 (-)	453	WP_000079154.1	universal stress protein	-
R4699_RS10570	-	2089172..2089466 (+)	295	Protein_2044	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=895522 R4699_RS10545 WP_000990607.1 2084665..2085675(+) (ccpA) [Streptococcus pneumoniae strain 16H2092]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=895522 R4699_RS10545 WP_000990607.1 2084665..2085675(+) (ccpA) [Streptococcus pneumoniae strain 16H2092]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568