Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R4699_RS00050 Genome accession   NZ_CP137105
Coordinates   11237..11857 (+) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain 16H2092     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 6237..16857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS00030 - 7924..8094 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  R4699_RS00035 - 8283..8702 (+) 420 Protein_6 helix-turn-helix domain-containing protein -
  R4699_RS00040 - 8857..10203 (+) 1347 WP_050104685.1 IS1380-like element ISSpn5 family transposase -
  R4699_RS00045 - 10396..10854 (+) 459 Protein_8 transcriptional regulator -
  R4699_RS00050 comM 11237..11857 (+) 621 WP_000839908.1 hypothetical protein Regulator
  R4699_RS00055 tsaE 11943..12386 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4699_RS00060 - 12376..12894 (+) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R4699_RS00065 brpA 12902..13918 (+) 1017 WP_044793036.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4699_RS00070 cinA 14003..15259 (+) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  R4699_RS00075 recA 15314..16480 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=895450 R4699_RS00050 WP_000839908.1 11237..11857(+) (comM) [Streptococcus pneumoniae strain 16H2092]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=895450 R4699_RS00050 WP_000839908.1 11237..11857(+) (comM) [Streptococcus pneumoniae strain 16H2092]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369