Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   R4708_RS02710 Genome accession   NZ_CP137104
Coordinates   559080..559817 (-) Length   245 a.a.
NCBI ID   WP_001219121.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LM     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 554080..564817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS02690 - 554400..555761 (+) 1362 WP_001069099.1 bacteriocin secretion accessory protein -
  R4708_RS02695 blpC 555818..555973 (+) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  R4708_RS02700 - 556140..557486 (+) 1347 WP_001821303.1 IS1380-like element ISSpn5 family transposase -
  R4708_RS02705 - 557726..559066 (-) 1341 WP_001028654.1 sensor histidine kinase -
  R4708_RS02710 comE/blpR 559080..559817 (-) 738 WP_001219121.1 response regulator transcription factor Regulator
  R4708_RS02715 - 559822..560160 (-) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  R4708_RS02720 - 560436..560765 (+) 330 WP_000132572.1 hypothetical protein -
  R4708_RS02725 - 560933..561982 (-) 1050 WP_000653766.1 ABC transporter permease -
  R4708_RS02730 pptA 561979..562710 (-) 732 WP_000889919.1 ABC transporter ATP-binding protein Regulator
  R4708_RS02735 - 562778..563188 (+) 411 WP_001278301.1 HIT family protein -
  R4708_RS02740 - 563198..563485 (+) 288 WP_000777760.1 hypothetical protein -
  R4708_RS02745 - 563647..563886 (+) 240 WP_001812223.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28740.91 Da        Isoelectric Point: 6.4140

>NTDB_id=895381 R4708_RS02710 WP_001219121.1 559080..559817(-) (comE/blpR) [Streptococcus pneumoniae strain LM]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=895381 R4708_RS02710 WP_001219121.1 559080..559817(-) (comE/blpR) [Streptococcus pneumoniae strain LM]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCTGAAGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCTTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGAATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAATATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCTCCCAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAACCCCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTTTTTCCCAATGGTGGAAGTTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.321

99.184

0.539
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38