Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4703_RS04545 Genome accession   NZ_CP137100
Coordinates   832805..833758 (-) Length   317 a.a.
NCBI ID   WP_000345122.1    Uniprot ID   A0A0I7TJC1
Organism   Streptococcus pneumoniae strain LYP     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 827805..838758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4703_RS04515 - 828566..829189 (-) 624 WP_000932654.1 hypothetical protein -
  R4703_RS04520 jag 829240..830226 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  R4703_RS04525 - 830245..831069 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  R4703_RS04530 rnpA 831044..831415 (-) 372 WP_000739244.1 ribonuclease P protein component -
  R4703_RS04535 - 831432..831563 (-) 132 WP_000768904.1 hypothetical protein -
  R4703_RS04540 - 831564..832754 (-) 1191 WP_000167770.1 acetate kinase -
  R4703_RS04545 comYH 832805..833758 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  R4703_RS04550 - 833819..834413 (-) 595 Protein_870 class I SAM-dependent methyltransferase -
  R4703_RS04555 comGG/cglG 834550..834963 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4703_RS04560 comGF/cglF 834941..835402 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4703_RS04565 comGE/cglE 835365..835667 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4703_RS04570 comGD/cglD 835630..836034 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4703_RS04575 comGC/cglC 836027..836293 (-) 267 WP_050129046.1 competence type IV pilus major pilin ComGC Machinery gene
  R4703_RS04580 - 836295..836552 (-) 258 WP_000698513.1 hypothetical protein -
  R4703_RS04585 - 836784..837740 (-) 957 WP_219576515.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R4703_RS04590 - 837743..838078 (-) 336 WP_050200954.1 phage holin -
  R4703_RS04595 - 838082..838381 (-) 300 WP_001811580.1 hypothetical protein -
  R4703_RS04600 - 838390..838740 (-) 351 WP_000852245.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35745.94 Da        Isoelectric Point: 4.2706

>NTDB_id=895096 R4703_RS04545 WP_000345122.1 832805..833758(-) (comYH) [Streptococcus pneumoniae strain LYP]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSNLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895096 R4703_RS04545 WP_000345122.1 832805..833758(-) (comYH) [Streptococcus pneumoniae strain LYP]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTTATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTAATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0I7TJC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

53.994

98.738

0.533
  comYH Streptococcus mutans UA159

53.674

98.738

0.53