Detailed information NTG0895093

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R4703_RS04255
• Genome accession: NZ_CP137100
• Coordinates: 785998..787008 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain LYP
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 780998..792008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4703_RS04230	-	782253..782546 (-)	294	WP_000977371.1	hypothetical protein	-
R4703_RS04235	-	782708..783160 (+)	453	WP_000079148.1	universal stress protein	-
R4703_RS04240	-	783195..784583 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
R4703_RS04245	-	784649..785611 (+)	963	WP_001124783.1	asparaginase	-
R4703_RS04250	-	785608..785934 (-)	327	WP_050201059.1	hypothetical protein	-
R4703_RS04255	ccpA	785998..787008 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R4703_RS04260	-	787433..788032 (-)	600	WP_000866724.1	response regulator transcription factor	-
R4703_RS04265	-	788034..789131 (-)	1098	WP_000893548.1	sensor histidine kinase	-
R4703_RS04270	-	789131..789868 (-)	738	WP_000832836.1	ABC transporter permease	-
R4703_RS04275	-	789870..790754 (-)	885	WP_050201058.1	ABC transporter ATP-binding protein	-
R4703_RS04280	-	790741..790935 (-)	195	WP_000820189.1	hypothetical protein	-
R4703_RS04285	-	790932..791138 (-)	207	Protein_831	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=895093 R4703_RS04255 WP_000990607.1 785998..787008(-) (ccpA) [Streptococcus pneumoniae strain LYP]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=895093 R4703_RS04255 WP_000990607.1 785998..787008(-) (ccpA) [Streptococcus pneumoniae strain LYP]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568