Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AAVB74_RS01310 Genome accession   NZ_CP154920
Coordinates   226061..227263 (+) Length   400 a.a.
NCBI ID   WP_021481077.1    Uniprot ID   -
Organism   Bacillus subtilis strain FUA2232     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 221061..232263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAVB74_RS01290 (AAVB74_01290) walK 221142..222977 (+) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -
  AAVB74_RS01295 (AAVB74_01295) walH 222967..224334 (+) 1368 WP_217019889.1 WalRK two-component regulatory system regulator WalH -
  AAVB74_RS01300 (AAVB74_01300) walI 224321..225163 (+) 843 WP_015250811.1 WalRK two-component regulatory system regulator WalI -
  AAVB74_RS01305 (AAVB74_01305) vicX 225185..225979 (+) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  AAVB74_RS01310 (AAVB74_01310) htrA 226061..227263 (+) 1203 WP_021481077.1 serine protease HtrC Regulator
  AAVB74_RS01315 (AAVB74_01315) - 227284..227413 (+) 130 Protein_226 hypothetical protein -
  AAVB74_RS01320 (AAVB74_01320) - 227410..227910 (-) 501 WP_015250813.1 PepSY domain-containing protein -
  AAVB74_RS01325 (AAVB74_01325) - 228071..228970 (-) 900 WP_332603843.1 PepSY domain-containing protein -
  AAVB74_RS01330 (AAVB74_01330) - 229182..229865 (+) 684 WP_038428106.1 response regulator transcription factor -
  AAVB74_RS01335 (AAVB74_01335) - 229862..231328 (+) 1467 WP_046381472.1 HAMP domain-containing sensor histidine kinase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.3354

>NTDB_id=895063 AAVB74_RS01310 WP_021481077.1 226061..227263(+) (htrA) [Bacillus subtilis strain FUA2232]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=895063 AAVB74_RS01310 WP_021481077.1 226061..227263(+) (htrA) [Bacillus subtilis strain FUA2232]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACTAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGATCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTCGATGT
CATCACGGAATTTGACGGTTACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(185-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373