Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4714_RS04290 Genome accession   NZ_CP137099
Coordinates   797044..797346 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20824-4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 792044..802346
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4714_RS04255 rnpA 792725..793096 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R4714_RS04260 - 793113..793244 (-) 132 WP_000768904.1 hypothetical protein -
  R4714_RS04265 - 793245..794435 (-) 1191 WP_000167766.1 acetate kinase -
  R4714_RS04270 comYH 794486..795439 (-) 954 WP_000345130.1 class I SAM-dependent methyltransferase Machinery gene
  R4714_RS04275 - 795500..796094 (-) 595 Protein_810 class I SAM-dependent methyltransferase -
  R4714_RS04280 comGG/cglG 796250..796642 (-) 393 WP_219576921.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4714_RS04285 comGF/cglF 796620..797081 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4714_RS04290 comGE/cglE 797044..797346 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4714_RS04295 comGD/cglD 797309..797713 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4714_RS04300 comGC/cglC 797706..797972 (-) 267 WP_000962022.1 competence type IV pilus major pilin ComGC Machinery gene
  R4714_RS04305 - 797974..798231 (-) 258 WP_000698512.1 hypothetical protein -
  R4714_RS04310 - 798502..799458 (-) 957 WP_057524567.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R4714_RS04315 - 799462..799794 (-) 333 WP_317769868.1 phage holin -
  R4714_RS04320 - 799798..800097 (-) 300 WP_001811580.1 hypothetical protein -
  R4714_RS04325 - 800106..800456 (-) 351 WP_000852245.1 hypothetical protein -
  R4714_RS04330 - 800459..800662 (-) 204 WP_001091112.1 hypothetical protein -
  R4714_RS04335 - 800643..800759 (-) 117 WP_001063633.1 hypothetical protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=895020 R4714_RS04290 WP_000413382.1 797044..797346(-) (comGE/cglE) [Streptococcus pneumoniae strain 20824-4]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=895020 R4714_RS04290 WP_000413382.1 797044..797346(-) (comGE/cglE) [Streptococcus pneumoniae strain 20824-4]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4