Detailed information NTG0894850

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: AAYR26_RS16740
• Genome accession: NZ_CP154901
• Coordinates: 3095978..3098587 (-)
• Length: 869 a.a.
• NCBI ID: WP_011197985.1
• Uniprot ID: Q65JE2
• Organism: Bacillus licheniformis strain FUA2146
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 3090978..3103587

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYR26_RS16715 (AAYR26_16720)	-	3091988..3092425 (-)	438	WP_011201654.1	hypothetical protein	-
AAYR26_RS16720 (AAYR26_16725)	-	3092481..3092729 (-)	249	WP_080508521.1	HNH/endonuclease VII fold putative polymorphic toxin	-
AAYR26_RS16725 (AAYR26_16730)	-	3092726..3093253 (-)	528	WP_003181977.1	pre-toxin TG domain-containing protein	-
AAYR26_RS16730 (AAYR26_16735)	-	3093435..3093716 (-)	282	WP_003181975.1	putative quinol monooxygenase	-
AAYR26_RS16735 (AAYR26_16740)	hexB	3094050..3095960 (-)	1911	WP_003181972.1	DNA mismatch repair endonuclease MutL	Machinery gene
AAYR26_RS16740 (AAYR26_16745)	hexA	3095978..3098587 (-)	2610	WP_011197985.1	DNA mismatch repair protein MutS	Machinery gene
AAYR26_RS16745 (AAYR26_16750)	cotE	3098698..3099246 (-)	549	WP_003181968.1	outer spore coat protein CotE	-
AAYR26_RS16750 (AAYR26_16755)	ymcA	3099489..3099920 (-)	432	WP_003181967.1	RicAFT regulatory complex protein RicA family protein	Regulator
AAYR26_RS16755 (AAYR26_16760)	miaB	3099922..3101451 (-)	1530	WP_003181965.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
AAYR26_RS16760 (AAYR26_16765)	-	3101595..3102770 (-)	1176	WP_009328481.1	glycine C-acetyltransferase	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98514.94 Da
• Isoelectric Point: 5.3661

>NTDB_id=894850 AAYR26_RS16740 WP_011197985.1 3095978..3098587(-) (hexA) [Bacillus licheniformis strain FUA2146]
MAGYTPMIQQYLKIKAEYQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGSSERIPMCGVPYHSCSSYIEQLIKK
GYKVAICEQVEDPKSAKGVVKREVVQLITPGTVMDGKGIHENENNFIASVSKFQHTYGLAFSDLTTGENLVTAIERLDDV
VSEIYSVGAREIVVSRNLDEKDVAMLKERCGATISFEDEQADEVPGIVNGLGSKELVDTFMRLYVYLKRTQKRSLDHLQN
VQAYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRKGQIEERQEIVETLIAHLF
EREDLRERLKEVYDLERLAGRVAYGNVNARDLIQLKESLKQVPAIKQLVGSLDHPKAKARAEKIDPCGDLLNLLEDALYE
NPPLSLKEGNLIKDGYHAKLDEYRDASKNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANIHLLEEGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFSELRSKVKEYIPRLQQLAKMMSELDVLQCFATISENRHYVKPEF
SDDVVQVIDGRHPVVEKVMDSQSYVPNSCEMGKGRQMLLITGPNMSGKSTYMRQMALISILAQIGCFVPAKKAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVHATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHEHIGAKTLFSTHYHEL
TSLEEKLDDLKNVHVRAEEYEGKVVFLHQIKEGAADKSYGIHVAQLAELPDGLISRAKTILKELESGAKEAAPSTAPNMV
KEAAEEAAATVADQPAQLSFFETDKPIEKETKLSKKEQAVLAEFKAMDLLDMTPIQVMNELYRLQKKLK

Nucleotide

• Length: 2610 bp

>NTDB_id=894850 AAYR26_RS16740 WP_011197985.1 3095978..3098587(-) (hexA) [Bacillus licheniformis strain FUA2146]
ATGGCAGGCTACACGCCTATGATACAGCAATATTTAAAGATTAAGGCAGAGTATCAGGATGCCTTTTTATTTTTTCGTCT
TGGCGACTTTTATGAGATGTTTTTTGAAGATGCAAAAAAGGCGTCTCAGGAGCTCGAAATCACGCTGACGAGCAGGGACG
GAGGATCAAGCGAAAGAATCCCGATGTGCGGGGTTCCTTATCATTCCTGCTCTTCGTATATCGAACAGCTCATTAAAAAA
GGCTATAAAGTCGCGATCTGTGAACAGGTGGAGGACCCTAAATCGGCCAAAGGAGTCGTCAAAAGGGAAGTCGTGCAGCT
GATCACACCCGGCACCGTGATGGACGGCAAAGGGATTCATGAAAATGAAAACAACTTTATCGCCTCTGTCAGTAAATTTC
AGCATACATACGGGCTCGCTTTTTCTGATTTGACGACGGGCGAGAATTTAGTAACGGCTATCGAAAGGCTTGATGATGTC
GTTTCCGAGATTTACTCTGTCGGAGCAAGGGAAATCGTCGTCAGCCGCAACCTTGACGAGAAAGACGTCGCAATGCTGAA
AGAGCGCTGCGGCGCCACGATCTCTTTCGAGGATGAACAAGCGGATGAAGTGCCTGGCATTGTGAACGGACTGGGGTCCA
AAGAGCTTGTCGATACGTTTATGAGGCTTTACGTCTACTTGAAGCGGACGCAGAAAAGAAGCCTCGACCACCTTCAAAAC
GTTCAGGCCTACGAGCTCGAAGAAGCGATGAAAATCGATTTGTACTCGAAACGCAATCTTGAACTGACGGAAACGATCCG
TTCGAAAAACAAAAAAGGCTCGCTTCTTTGGCTTTTGGATGAAACGAAAACGGCCATGGGAGGGCGGCTGTTAAAGCAAT
GGATCGACAGGCCGCTGATCAGAAAGGGACAGATCGAAGAGCGCCAGGAAATCGTTGAAACGCTGATCGCCCATCTGTTT
GAGCGGGAAGATTTGCGCGAACGGCTGAAGGAAGTATACGACCTCGAGCGGCTCGCCGGAAGGGTCGCATACGGCAACGT
CAACGCCAGAGATTTGATCCAGCTGAAGGAATCGCTGAAACAAGTCCCGGCCATCAAACAGCTTGTCGGCTCCCTCGACC
ATCCGAAAGCAAAAGCGCGCGCCGAGAAAATCGATCCGTGCGGCGATCTTTTGAATCTTTTGGAAGACGCGCTATACGAG
AATCCGCCTCTTTCATTAAAAGAGGGGAACTTAATCAAAGACGGCTACCACGCGAAACTGGATGAATACAGGGACGCAAG
CAAGAACGGAAAAGACTGGATCGCAAGGCTTGAGCAGCAGGAACGCGAGTACACGGGAATCCGCTCTTTAAAAGTCGGCT
TTAACAAGGTGTTCGGCTATTATATTGAAGTGACGAAAGCGAACATCCATCTGCTTGAAGAAGGCCGCTATGAACGGAAG
CAGACGCTGACCAATGCAGAACGCTACATCACGCCGGAGCTGAAAGAAAAAGAAGCCCTGATTCTCGAAGCGGAAAACAA
TATTTGCGAGCTGGAGTATGAGCTGTTTTCCGAGCTTCGCAGCAAGGTGAAGGAATATATCCCGCGCTTGCAGCAGCTGG
CAAAAATGATGAGCGAGCTTGATGTGCTCCAATGTTTTGCGACGATCAGCGAAAACCGGCACTATGTTAAGCCGGAGTTT
TCCGATGATGTCGTTCAGGTGATCGACGGACGGCATCCGGTCGTAGAAAAGGTGATGGACAGCCAGTCTTACGTTCCGAA
CAGCTGTGAAATGGGCAAAGGCAGGCAGATGCTTTTAATCACCGGGCCGAATATGTCCGGGAAAAGCACGTATATGAGAC
AGATGGCGCTGATCTCCATTTTGGCGCAGATCGGCTGCTTTGTTCCTGCGAAAAAAGCGGTGCTGCCGATCTTTGATCAG
ATCTTTACGAGAATTGGCGCAGCGGATGATCTTATATCCGGACAGAGCACGTTTATGGTGGAAATGCTTGAAGCCAAAAA
CGCGATCGTCCATGCGACGAAAAACAGCTTGATTTTATTTGACGAAATCGGCCGGGGTACGTCCACTTACGACGGAATGG
CGCTTGCACAAGCGATCATCGAGTACGTTCACGAGCACATCGGCGCGAAGACTTTATTTTCCACTCACTACCACGAGCTG
ACGTCCCTTGAAGAAAAGCTGGACGATTTGAAGAATGTCCACGTTCGTGCGGAAGAATACGAAGGAAAGGTCGTTTTCCT
TCACCAGATAAAAGAAGGAGCAGCAGATAAAAGCTACGGTATCCATGTCGCGCAGCTGGCTGAATTGCCCGACGGTTTGA
TCAGCAGGGCGAAAACGATCCTGAAAGAACTTGAATCCGGCGCAAAAGAAGCCGCTCCATCAACGGCACCGAATATGGTA
AAAGAGGCGGCGGAAGAAGCCGCGGCGACTGTTGCAGATCAACCGGCCCAGCTGTCATTTTTTGAGACGGACAAGCCAAT
AGAAAAAGAGACGAAGCTCTCCAAAAAAGAGCAGGCTGTTTTAGCCGAATTTAAAGCGATGGATCTGCTCGATATGACGC
CTATACAAGTCATGAATGAACTGTACAGGCTGCAAAAAAAATTAAAGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-785)

• MutS domain III (MutS_III) (258-547)

• MutS domain I (MutS_I) (5-116)

• MutS domain II (MutS_II) (125-239)

• MutS family domain IV (MutS_IV) (415-506)

3D structure

• AlphaFold DB: Q65JE2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	49.017	99.54	0.488
mutS	Pseudomonas stutzeri strain ATCC 17587	37.528	100	0.381