Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   AAFU62_RS08325 Genome accession   NZ_CP154891
Coordinates   1716906..1717502 (-) Length   198 a.a.
NCBI ID   WP_053308677.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 318231     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1711906..1722502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFU62_RS08290 (AAFU62_08290) - 1711967..1712272 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  AAFU62_RS08295 (AAFU62_08295) ruvX 1712284..1712703 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  AAFU62_RS08300 (AAFU62_08300) - 1712700..1712969 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  AAFU62_RS08305 (AAFU62_08305) spx 1713082..1713480 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  AAFU62_RS08310 (AAFU62_08310) recA 1713772..1714908 (-) 1137 WP_023612576.1 recombinase RecA -
  AAFU62_RS08315 (AAFU62_08315) - 1714997..1716267 (-) 1271 Protein_1576 competence/damage-inducible protein A -
  AAFU62_RS08320 (AAFU62_08320) - 1716336..1716896 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  AAFU62_RS08325 (AAFU62_08325) ruvA 1716906..1717502 (-) 597 WP_053308677.1 Holliday junction branch migration protein RuvA Machinery gene
  AAFU62_RS08330 (AAFU62_08330) - 1717504..1718724 (-) 1221 WP_136268352.1 MFS transporter -
  AAFU62_RS08335 (AAFU62_08335) hexB 1718735..1720717 (-) 1983 WP_053308679.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21799.13 Da        Isoelectric Point: 6.2537

>NTDB_id=894325 AAFU62_RS08325 WP_053308677.1 1716906..1717502(-) (ruvA) [Streptococcus pyogenes strain 318231]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=894325 AAFU62_RS08325 WP_053308677.1 1716906..1717502(-) (ruvA) [Streptococcus pyogenes strain 318231]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424