Detailed information NTG0894133

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AAYT23_RS08910
• Genome accession: NZ_CP154877
• Coordinates: 1735175..1736086 (-)
• Length: 303 a.a.
• NCBI ID: WP_000904854.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20234295
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1730175..1741086

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT23_RS08885 (AAYT23_08870)	rsmA	1730399..1731271 (-)	873	WP_001216869.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
AAYT23_RS08890 (AAYT23_08875)	-	1731522..1731815 (-)	294	Protein_1736	hypothetical protein	-
AAYT23_RS08895 (AAYT23_08880)	-	1731808..1732449 (-)	642	WP_000565530.1	ABC transporter ATP-binding protein	-
AAYT23_RS08900 (AAYT23_08885)	-	1732451..1734481 (-)	2031	WP_000825277.1	bacteriocin-associated integral membrane family protein	-
AAYT23_RS08905 (AAYT23_08890)	-	1734558..1734854 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
AAYT23_RS08910 (AAYT23_08895)	comR	1735175..1736086 (-)	912	WP_000904854.1	helix-turn-helix domain-containing protein	Regulator
AAYT23_RS08915 (AAYT23_08900)	rnmV	1736158..1736718 (-)	561	WP_000660009.1	ribonuclease M5	-
AAYT23_RS08920 (AAYT23_08905)	-	1736718..1737491 (-)	774	WP_000575621.1	TatD family hydrolase	-
AAYT23_RS08925 (AAYT23_08910)	-	1737796..1738503 (-)	708	Protein_1743	DUF1542 domain-containing protein	-
AAYT23_RS08930 (AAYT23_08915)	rpmH	1738712..1738846 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
AAYT23_RS08935 (AAYT23_08920)	-	1738991..1740205 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
AAYT23_RS08940 (AAYT23_08925)	-	1740361..1740654 (-)	294	WP_000977369.1	hypothetical protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35509.76 Da
• Isoelectric Point: 4.4509

>NTDB_id=894133 AAYT23_RS08910 WP_000904854.1 1735175..1736086(-) (comR) [Streptococcus pneumoniae strain 20234295]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYDKEEEYDKKEACLEEIEDLFYEQLPNEEKVWFEATRATIDVIRSGQPEYGETVLDDYFKTIYDKELFLINELEV
INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACLDNLSSYDSLGAYIFSLNHIMEK
TQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSKLFADIIENSYLVTMLEKQWQEDLKKYL

Nucleotide

• Length: 912 bp

>NTDB_id=894133 AAYT23_RS08910 WP_000904854.1 1735175..1736086(-) (comR) [Streptococcus pneumoniae strain 20234295]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGATAAAGAAGAGGAGTATGATAAGAAAGAAGCGTGTTTGGAAGAGATAGAGGATTTATTTTA
TGAGCAACTTCCTAATGAGGAGAAAGTATGGTTTGAAGCTACTAGAGCAACGATAGATGTTATTCGAAGCGGACAACCAG
AATACGGGGAAACCGTACTGGACGATTATTTTAAAACAATTTATGATAAGGAATTGTTTTTGATAAATGAATTAGAAGTT
ATCAACTTATATTTTGCTATAGTGCTTACAAAGATAAAACAAGGTCAAAATCAGATTGAAGAAATTAACAGAATTCATTC
GTTTTTAGTTCGTTTGACAAATCATGTAGAATTAATTGCACCAGAATATCTGTTTGCTTTAAGTAACACTTTGTTTTCGG
GTCTAGCCTGTTTGGATAATTTGTCGTCTTATGATTCACTAGGAGCTTATATCTTTAGCCTTAATCATATAATGGAAAAA
ACACAAGATTTCCAGAAGAAACCAATTATATTAATGTTGGAGTGGAAATTATCTCTAATAATAAACAATGATTATGTTTC
TGCCGAACAGTTCTATCAGAAATCGAAGCTATTTGCTGATATAATAGAAAATTCTTATTTAGTTACTATGTTAGAAAAAC
AATGGCAAGAAGATTTAAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	38.851	97.69	0.38
comR	Streptococcus pyogenes MGAS8232	37.5	100	0.376
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363