Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | RJD36_RS04205 | Genome accession | NZ_CP136943 |
| Coordinates | 796139..798292 (+) | Length | 717 a.a. |
| NCBI ID | WP_317751482.1 | Uniprot ID | - |
| Organism | Streptococcus pasteurianus strain WUSP082 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 780186..823964 | 796139..798292 | within | 0 |
Gene organization within MGE regions
Location: 780186..823964
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RJD36_RS04115 (RJD36_04115) | - | 780186..780407 (+) | 222 | WP_168931723.1 | hypothetical protein | - |
| RJD36_RS04120 (RJD36_04120) | - | 780492..780773 (+) | 282 | WP_168931724.1 | hypothetical protein | - |
| RJD36_RS04125 (RJD36_04125) | - | 780790..780999 (+) | 210 | WP_205942886.1 | hypothetical protein | - |
| RJD36_RS04130 (RJD36_04130) | - | 781093..781377 (+) | 285 | WP_168931725.1 | hypothetical protein | - |
| RJD36_RS04135 (RJD36_04135) | - | 781577..782074 (+) | 498 | WP_168931726.1 | antirestriction protein ArdA | - |
| RJD36_RS04140 (RJD36_04140) | - | 782092..782595 (+) | 504 | WP_168931727.1 | antirestriction protein ArdA | - |
| RJD36_RS04145 (RJD36_04145) | - | 782698..783087 (+) | 390 | WP_168931729.1 | conjugal transfer protein | - |
| RJD36_RS04150 (RJD36_04150) | - | 783074..785524 (+) | 2451 | WP_317751480.1 | ATP-binding protein | - |
| RJD36_RS04155 (RJD36_04155) | - | 785521..787677 (+) | 2157 | WP_168931732.1 | CD3337/EF1877 family mobilome membrane protein | - |
| RJD36_RS04160 (RJD36_04160) | - | 787674..788672 (+) | 999 | WP_317751481.1 | lysozyme family protein | - |
| RJD36_RS04165 (RJD36_04165) | - | 788697..789596 (+) | 900 | WP_168931735.1 | conjugal transfer protein | - |
| RJD36_RS04170 (RJD36_04170) | - | 789719..789892 (+) | 174 | WP_168931737.1 | recombinase family protein | - |
| RJD36_RS04175 (RJD36_04175) | - | 790784..791350 (-) | 567 | WP_168931738.1 | hypothetical protein | - |
| RJD36_RS04180 (RJD36_04180) | - | 791663..792834 (+) | 1172 | Protein_758 | IS256-like element IS256 family transposase | - |
| RJD36_RS04185 (RJD36_04185) | - | 792967..793143 (-) | 177 | WP_168931740.1 | hypothetical protein | - |
| RJD36_RS04190 (RJD36_04190) | - | 793144..793359 (-) | 216 | WP_168931742.1 | bacteriocin | - |
| RJD36_RS04195 (RJD36_04195) | - | 793373..793603 (-) | 231 | WP_168931743.1 | Blp family class II bacteriocin | - |
| RJD36_RS04200 (RJD36_04200) | - | 794153..795323 (+) | 1171 | Protein_762 | IS256-like element IS256 family transposase | - |
| RJD36_RS04205 (RJD36_04205) | comA | 796139..798292 (+) | 2154 | WP_317751482.1 | peptide cleavage/export ABC transporter | Regulator |
| RJD36_RS04210 (RJD36_04210) | - | 798345..798506 (+) | 162 | WP_168931748.1 | hypothetical protein | - |
| RJD36_RS04215 (RJD36_04215) | - | 798506..798853 (+) | 348 | WP_317751483.1 | hypothetical protein | - |
| RJD36_RS04220 (RJD36_04220) | - | 798880..799818 (+) | 939 | WP_317751484.1 | GHKL domain-containing protein | - |
| RJD36_RS04225 (RJD36_04225) | - | 799818..800567 (+) | 750 | WP_205942887.1 | LytTR family DNA-binding domain-containing protein | - |
| RJD36_RS04230 (RJD36_04230) | - | 800876..802046 (+) | 1171 | Protein_768 | IS256-like element IS256 family transposase | - |
| RJD36_RS04235 (RJD36_04235) | - | 802550..802780 (+) | 231 | WP_010817848.1 | Blp family class II bacteriocin | - |
| RJD36_RS04240 (RJD36_04240) | - | 803317..804488 (-) | 1172 | Protein_770 | IS256 family transposase | - |
| RJD36_RS04245 (RJD36_04245) | - | 804669..804923 (+) | 255 | WP_168931751.1 | bacteriocin | - |
| RJD36_RS04250 (RJD36_04250) | - | 805205..805450 (+) | 246 | WP_240936356.1 | hypothetical protein | - |
| RJD36_RS04255 (RJD36_04255) | - | 805711..806139 (+) | 429 | WP_168931753.1 | RNA polymerase sigma factor | - |
| RJD36_RS04260 (RJD36_04260) | - | 806143..806382 (+) | 240 | WP_168931754.1 | helix-turn-helix domain-containing protein | - |
| RJD36_RS04265 (RJD36_04265) | - | 806541..807646 (+) | 1106 | WP_249551291.1 | IS3 family transposase | - |
| RJD36_RS04270 (RJD36_04270) | - | 807978..808217 (+) | 240 | WP_168931758.1 | DUF6870 family protein | - |
| RJD36_RS04275 (RJD36_04275) | - | 808280..810028 (+) | 1749 | WP_168931760.1 | recombinase family protein | - |
| RJD36_RS04280 (RJD36_04280) | - | 810055..810648 (+) | 594 | Protein_778 | ATP-binding cassette domain-containing protein | - |
| RJD36_RS04285 (RJD36_04285) | - | 810641..811378 (+) | 738 | WP_222819184.1 | lantibiotic ABC transporter permease | - |
| RJD36_RS04290 (RJD36_04290) | - | 811356..812042 (+) | 687 | WP_001033677.1 | hypothetical protein | - |
| RJD36_RS04295 (RJD36_04295) | - | 812109..812825 (+) | 717 | WP_001226539.1 | NisI/SpaI family lantibiotic immunity lipoprotein | - |
| RJD36_RS04300 (RJD36_04300) | - | 813093..813497 (+) | 405 | WP_000878635.1 | sigma-70 family RNA polymerase sigma factor | - |
| RJD36_RS04305 (RJD36_04305) | - | 813820..813948 (+) | 129 | WP_000438255.1 | SHOCT domain-containing protein | - |
| RJD36_RS04310 (RJD36_04310) | - | 814002..815792 (+) | 1791 | WP_117479704.1 | recombinase family protein | - |
| RJD36_RS04315 (RJD36_04315) | - | 815740..816060 (+) | 321 | Protein_785 | 23S rRNA (uracil-5-)-methyltransferase RumA | - |
| RJD36_RS04320 (RJD36_04320) | - | 816084..816321 (+) | 238 | Protein_786 | CD1845 family protein | - |
| RJD36_RS04325 (RJD36_04325) | - | 816341..816730 (+) | 390 | WP_019116047.1 | VOC family protein | - |
| RJD36_RS04330 (RJD36_04330) | - | 816835..817125 (+) | 291 | WP_117508725.1 | DUF3847 domain-containing protein | - |
| RJD36_RS04335 (RJD36_04335) | - | 817209..817403 (+) | 195 | WP_220432036.1 | transposon-encoded TnpW family protein | - |
| RJD36_RS04340 (RJD36_04340) | - | 817570..818136 (+) | 567 | WP_117479700.1 | GNAT family N-acetyltransferase | - |
| RJD36_RS04345 (RJD36_04345) | - | 818244..818540 (+) | 297 | Protein_791 | DUF3847 domain-containing protein | - |
| RJD36_RS04350 (RJD36_04350) | - | 818958..819128 (+) | 171 | Protein_792 | MobA/MobL family protein | - |
| RJD36_RS04355 (RJD36_04355) | - | 819198..820303 (+) | 1106 | WP_249551291.1 | IS3 family transposase | - |
| RJD36_RS04360 (RJD36_04360) | - | 820534..820731 (+) | 198 | WP_142917672.1 | hypothetical protein | - |
| RJD36_RS04365 (RJD36_04365) | - | 820724..820999 (+) | 276 | WP_240208137.1 | recombinase family protein | - |
| RJD36_RS12535 | - | 821204..821620 (+) | 417 | Protein_796 | recombinase family protein | - |
| RJD36_RS04380 (RJD36_04380) | - | 821693..822160 (+) | 468 | WP_259294249.1 | zinc ribbon domain-containing protein | - |
| RJD36_RS04385 (RJD36_04385) | - | 822270..822599 (+) | 330 | Protein_798 | NUDIX domain-containing protein | - |
| RJD36_RS04390 (RJD36_04390) | - | 822762..823964 (-) | 1203 | WP_117479995.1 | ROK family transcriptional regulator | - |
Sequence
Protein
Download Length: 717 a.a. Molecular weight: 81295.26 Da Isoelectric Point: 9.0389
>NTDB_id=893544 RJD36_RS04205 WP_317751482.1 796139..798292(+) (comA) [Streptococcus pasteurianus strain WUSP082]
MRFKKCHYRSQVDMKDCGVATLAMILEYYGSYYSLATLREMAKTTQDGTTALGLIKVAEDLHFNTQAIQADMSLFDVENL
SFPFIAYVIKNETLLHYYTVIGCDKKNIHIADPDSSVGITKMSRKQFEKEWTGVTLFFTPSNCYKPYKEKKVGLWSFIPV
LKKQKVLISQIIGATLFITFINISGSYYLQAIIDNYIPNQMFHVLGIISIGLIIGYTIQQLVSYVQSQLLMILGQRLSIE
IILSYIKHVLHLPLSFFSTRRTGEIVSRFTDANAIIEALASTVLSVFLDVSVAIIVAVILCLQHPLLFLISILSLPIYTL
IVFLFMKPFERMNQEVMETNAKLSSSIIEDINGIETLKALSSEDTSYQKIDKEFTVHLKKSFTYYRSENIQKAIKILLHL
LLNVFILWTGSKLVMSNQMTLGQLITFNTMLVYFTNPLENIVNLQTKLQKAHVANARLNEVYQIKSEFLSQQPMIDFKEW
KKTISFKKVSFRYGYGSEVLSKIDFTIEKGSKVAFVGISGSGKTTLAKLLVNFYEPTHGEITLDHINLKKIDKKSLRHLI
TYLPQQPYIFNGTILENLLLGAPKDTTQKDIIEVLNFVELNTDISRLPMQLQTELTSDGTELSGGQKQRIALARALLTKS
PILILDEATSSLDVLTEKKIIDNLLALDKTILFIAHRLTIAERADRIIVLDKGQLIEDGPHETLLKKGGFYTHLMNS
MRFKKCHYRSQVDMKDCGVATLAMILEYYGSYYSLATLREMAKTTQDGTTALGLIKVAEDLHFNTQAIQADMSLFDVENL
SFPFIAYVIKNETLLHYYTVIGCDKKNIHIADPDSSVGITKMSRKQFEKEWTGVTLFFTPSNCYKPYKEKKVGLWSFIPV
LKKQKVLISQIIGATLFITFINISGSYYLQAIIDNYIPNQMFHVLGIISIGLIIGYTIQQLVSYVQSQLLMILGQRLSIE
IILSYIKHVLHLPLSFFSTRRTGEIVSRFTDANAIIEALASTVLSVFLDVSVAIIVAVILCLQHPLLFLISILSLPIYTL
IVFLFMKPFERMNQEVMETNAKLSSSIIEDINGIETLKALSSEDTSYQKIDKEFTVHLKKSFTYYRSENIQKAIKILLHL
LLNVFILWTGSKLVMSNQMTLGQLITFNTMLVYFTNPLENIVNLQTKLQKAHVANARLNEVYQIKSEFLSQQPMIDFKEW
KKTISFKKVSFRYGYGSEVLSKIDFTIEKGSKVAFVGISGSGKTTLAKLLVNFYEPTHGEITLDHINLKKIDKKSLRHLI
TYLPQQPYIFNGTILENLLLGAPKDTTQKDIIEVLNFVELNTDISRLPMQLQTELTSDGTELSGGQKQRIALARALLTKS
PILILDEATSSLDVLTEKKIIDNLLALDKTILFIAHRLTIAERADRIIVLDKGQLIEDGPHETLLKKGGFYTHLMNS
Nucleotide
Download Length: 2154 bp
>NTDB_id=893544 RJD36_RS04205 WP_317751482.1 796139..798292(+) (comA) [Streptococcus pasteurianus strain WUSP082]
ATGAGATTTAAGAAATGTCATTATCGGTCGCAAGTAGATATGAAAGACTGTGGCGTGGCTACTCTCGCAATGATACTTGA
ATATTATGGTTCGTATTATTCTTTGGCAACATTAAGAGAAATGGCAAAAACAACACAAGACGGAACTACTGCATTAGGAC
TTATTAAAGTAGCGGAAGACCTACATTTTAATACACAAGCTATTCAAGCAGATATGTCGCTATTTGATGTAGAAAATCTA
TCATTTCCTTTTATTGCATATGTAATAAAGAATGAAACACTTTTACATTATTATACGGTAATAGGCTGTGATAAAAAGAA
TATTCATATTGCTGATCCAGATTCTTCTGTAGGAATAACGAAAATGTCTCGTAAACAGTTTGAGAAAGAATGGACAGGCG
TTACATTATTTTTTACACCGTCTAATTGTTATAAGCCATATAAGGAAAAGAAAGTTGGCTTATGGTCTTTTATACCTGTT
TTGAAGAAACAAAAAGTACTGATTAGTCAGATTATTGGGGCTACTTTATTTATAACTTTTATCAATATTAGTGGTTCTTA
TTACTTACAAGCTATTATTGATAATTATATCCCAAATCAAATGTTTCATGTATTAGGAATTATTTCTATAGGATTGATCA
TTGGTTATACGATACAACAATTAGTGTCATATGTTCAGTCACAATTGTTAATGATATTAGGACAACGTCTATCTATTGAG
ATTATTTTGTCTTATATCAAGCATGTTTTACATTTACCACTCTCTTTTTTCTCAACCCGAAGAACTGGAGAAATTGTTTC
TAGATTTACAGACGCAAATGCAATCATAGAGGCTTTAGCGAGTACAGTATTATCTGTCTTTTTAGATGTTTCTGTTGCTA
TAATCGTAGCAGTTATTTTATGTTTACAACATCCTCTATTATTTTTGATTAGTATTCTATCACTGCCGATTTATACTTTA
ATTGTCTTCCTATTCATGAAGCCATTTGAAAGAATGAATCAAGAGGTCATGGAAACTAATGCAAAATTATCGTCTTCTAT
TATTGAAGATATAAATGGAATAGAAACTCTTAAAGCATTATCAAGTGAAGATACAAGCTATCAAAAAATAGATAAAGAAT
TTACCGTGCATTTAAAGAAATCATTCACTTACTATCGAAGTGAAAACATACAGAAAGCAATAAAAATTTTACTGCATTTA
TTATTGAATGTATTTATTTTATGGACAGGATCAAAACTTGTTATGAGTAATCAAATGACTTTAGGACAATTGATTACATT
CAATACCATGTTAGTATATTTTACAAATCCTTTAGAGAATATTGTGAATTTACAAACAAAACTACAAAAAGCACATGTGG
CAAATGCACGATTAAATGAAGTTTATCAAATTAAATCAGAGTTTTTATCTCAACAGCCAATGATTGATTTCAAAGAGTGG
AAAAAGACAATTTCATTTAAAAAAGTAAGTTTTCGATATGGCTATGGATCAGAGGTTTTAAGCAAAATTGATTTTACCAT
AGAAAAAGGAAGTAAAGTAGCTTTTGTTGGTATATCGGGGTCTGGTAAAACAACTTTGGCAAAGCTATTAGTAAATTTTT
ATGAACCTACTCATGGAGAAATAACATTAGATCATATAAACTTAAAGAAAATAGATAAGAAAAGCTTACGACATTTGATT
ACTTATCTTCCTCAACAGCCGTATATATTTAATGGAACAATTTTAGAAAATTTACTATTAGGTGCACCAAAAGATACAAC
GCAAAAGGATATTATAGAAGTATTAAATTTTGTTGAATTGAATACAGATATCTCTCGATTGCCTATGCAATTACAGACAG
AATTAACCTCTGACGGTACAGAATTATCTGGTGGACAAAAACAAAGAATTGCTTTAGCCAGAGCATTGCTTACAAAATCA
CCTATATTAATTTTAGATGAAGCAACAAGTAGTTTAGATGTATTAACCGAGAAAAAAATAATTGACAATCTATTAGCATT
AGATAAGACCATCTTATTCATTGCTCACCGTTTAACAATTGCGGAACGAGCAGATCGTATCATTGTGTTAGATAAAGGAC
AACTCATTGAAGATGGTCCGCATGAAACACTGCTAAAAAAAGGAGGTTTCTATACTCATTTAATGAATAGTTAA
ATGAGATTTAAGAAATGTCATTATCGGTCGCAAGTAGATATGAAAGACTGTGGCGTGGCTACTCTCGCAATGATACTTGA
ATATTATGGTTCGTATTATTCTTTGGCAACATTAAGAGAAATGGCAAAAACAACACAAGACGGAACTACTGCATTAGGAC
TTATTAAAGTAGCGGAAGACCTACATTTTAATACACAAGCTATTCAAGCAGATATGTCGCTATTTGATGTAGAAAATCTA
TCATTTCCTTTTATTGCATATGTAATAAAGAATGAAACACTTTTACATTATTATACGGTAATAGGCTGTGATAAAAAGAA
TATTCATATTGCTGATCCAGATTCTTCTGTAGGAATAACGAAAATGTCTCGTAAACAGTTTGAGAAAGAATGGACAGGCG
TTACATTATTTTTTACACCGTCTAATTGTTATAAGCCATATAAGGAAAAGAAAGTTGGCTTATGGTCTTTTATACCTGTT
TTGAAGAAACAAAAAGTACTGATTAGTCAGATTATTGGGGCTACTTTATTTATAACTTTTATCAATATTAGTGGTTCTTA
TTACTTACAAGCTATTATTGATAATTATATCCCAAATCAAATGTTTCATGTATTAGGAATTATTTCTATAGGATTGATCA
TTGGTTATACGATACAACAATTAGTGTCATATGTTCAGTCACAATTGTTAATGATATTAGGACAACGTCTATCTATTGAG
ATTATTTTGTCTTATATCAAGCATGTTTTACATTTACCACTCTCTTTTTTCTCAACCCGAAGAACTGGAGAAATTGTTTC
TAGATTTACAGACGCAAATGCAATCATAGAGGCTTTAGCGAGTACAGTATTATCTGTCTTTTTAGATGTTTCTGTTGCTA
TAATCGTAGCAGTTATTTTATGTTTACAACATCCTCTATTATTTTTGATTAGTATTCTATCACTGCCGATTTATACTTTA
ATTGTCTTCCTATTCATGAAGCCATTTGAAAGAATGAATCAAGAGGTCATGGAAACTAATGCAAAATTATCGTCTTCTAT
TATTGAAGATATAAATGGAATAGAAACTCTTAAAGCATTATCAAGTGAAGATACAAGCTATCAAAAAATAGATAAAGAAT
TTACCGTGCATTTAAAGAAATCATTCACTTACTATCGAAGTGAAAACATACAGAAAGCAATAAAAATTTTACTGCATTTA
TTATTGAATGTATTTATTTTATGGACAGGATCAAAACTTGTTATGAGTAATCAAATGACTTTAGGACAATTGATTACATT
CAATACCATGTTAGTATATTTTACAAATCCTTTAGAGAATATTGTGAATTTACAAACAAAACTACAAAAAGCACATGTGG
CAAATGCACGATTAAATGAAGTTTATCAAATTAAATCAGAGTTTTTATCTCAACAGCCAATGATTGATTTCAAAGAGTGG
AAAAAGACAATTTCATTTAAAAAAGTAAGTTTTCGATATGGCTATGGATCAGAGGTTTTAAGCAAAATTGATTTTACCAT
AGAAAAAGGAAGTAAAGTAGCTTTTGTTGGTATATCGGGGTCTGGTAAAACAACTTTGGCAAAGCTATTAGTAAATTTTT
ATGAACCTACTCATGGAGAAATAACATTAGATCATATAAACTTAAAGAAAATAGATAAGAAAAGCTTACGACATTTGATT
ACTTATCTTCCTCAACAGCCGTATATATTTAATGGAACAATTTTAGAAAATTTACTATTAGGTGCACCAAAAGATACAAC
GCAAAAGGATATTATAGAAGTATTAAATTTTGTTGAATTGAATACAGATATCTCTCGATTGCCTATGCAATTACAGACAG
AATTAACCTCTGACGGTACAGAATTATCTGGTGGACAAAAACAAAGAATTGCTTTAGCCAGAGCATTGCTTACAAAATCA
CCTATATTAATTTTAGATGAAGCAACAAGTAGTTTAGATGTATTAACCGAGAAAAAAATAATTGACAATCTATTAGCATT
AGATAAGACCATCTTATTCATTGCTCACCGTTTAACAATTGCGGAACGAGCAGATCGTATCATTGTGTTAGATAAAGGAC
AACTCATTGAAGATGGTCCGCATGAAACACTGCTAAAAAAAGGAGGTTTCTATACTCATTTAATGAATAGTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus pneumoniae Rx1 |
65.83 |
100 |
0.658 |
| comA | Streptococcus pneumoniae D39 |
65.83 |
100 |
0.658 |
| comA | Streptococcus pneumoniae R6 |
65.83 |
100 |
0.658 |
| comA | Streptococcus mitis NCTC 12261 |
65.83 |
100 |
0.658 |
| comA | Streptococcus mitis SK321 |
65.83 |
100 |
0.658 |
| comA | Streptococcus pneumoniae TIGR4 |
65.69 |
100 |
0.657 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
64.156 |
100 |
0.642 |
| comA/nlmT | Streptococcus mutans UA159 |
54.951 |
100 |
0.55 |