Detailed information NTG0893508

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AAIS09_RS09190
• Genome accession: NZ_CP154595
• Coordinates: 1812282..1813181 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904870.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain serotype 4
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1807282..1818181

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAIS09_RS09165 (AAIS09_09150)	rsmA	1807612..1808484 (-)	873	WP_001216878.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
AAIS09_RS09170 (AAIS09_09155)	-	1808615..1808923 (-)	309	WP_000333257.1	hypothetical protein	-
AAIS09_RS09175 (AAIS09_09160)	-	1808916..1809557 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
AAIS09_RS09180 (AAIS09_09165)	-	1809559..1811589 (-)	2031	WP_061813569.1	bacteriocin-associated integral membrane family protein	-
AAIS09_RS09185 (AAIS09_09170)	-	1811666..1811962 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
AAIS09_RS09190 (AAIS09_09175)	comR	1812282..1813181 (-)	900	WP_000904870.1	helix-turn-helix transcriptional regulator	Regulator
AAIS09_RS09195 (AAIS09_09180)	rnmV	1813253..1813813 (-)	561	WP_000660019.1	ribonuclease M5	-
AAIS09_RS09200 (AAIS09_09185)	-	1813813..1814586 (-)	774	WP_061813568.1	TatD family hydrolase	-
AAIS09_RS09205 (AAIS09_09190)	-	1814891..1815862 (-)	972	Protein_1800	DUF1542 domain-containing protein	-
AAIS09_RS09210 (AAIS09_09195)	rpmH	1816068..1816202 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
AAIS09_RS09215 (AAIS09_09200)	-	1816347..1817561 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
AAIS09_RS09220 (AAIS09_09205)	-	1817717..1818010 (-)	294	WP_061813566.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35351.12 Da
• Isoelectric Point: 4.8336

>NTDB_id=893508 AAIS09_RS09190 WP_000904870.1 1812282..1813181(-) (comR) [Streptococcus pneumoniae strain serotype 4]
MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=893508 AAIS09_RS09190 WP_000904870.1 1812282..1813181(-) (comR) [Streptococcus pneumoniae strain serotype 4]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAGTTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361