Detailed information NTG0893210

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R1Y14_RS00835
• Genome accession: NZ_CP136899
• Coordinates: 135495..135956 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250534.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ST62
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 130495..140956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R1Y14_RS00800 (R1Y14_00800)	-	130799..131623 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
R1Y14_RS00805 (R1Y14_00805)	rnpA	131598..131969 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R1Y14_RS00810 (R1Y14_00810)	-	131986..132117 (-)	132	WP_000768904.1	hypothetical protein	-
R1Y14_RS00815 (R1Y14_00815)	-	132118..133308 (-)	1191	WP_000167766.1	acetate kinase	-
R1Y14_RS00820 (R1Y14_00820)	comYH	133359..134312 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
R1Y14_RS00825 (R1Y14_00825)	-	134373..134967 (-)	595	Protein_137	class I SAM-dependent methyltransferase	-
R1Y14_RS00830 (R1Y14_00830)	comGG/cglG	135104..135517 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
R1Y14_RS00835 (R1Y14_00835)	comGF/cglF	135495..135956 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
R1Y14_RS00840 (R1Y14_00840)	comGE/cglE	135919..136221 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R1Y14_RS00845 (R1Y14_00845)	comGD/cglD	136184..136588 (-)	405	WP_000588028.1	competence type IV pilus minor pilin ComGD	Machinery gene
R1Y14_RS00850 (R1Y14_00850)	comGC/cglC	136581..136907 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
R1Y14_RS00855 (R1Y14_00855)	comGB/cglB	136909..137925 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
R1Y14_RS00860 (R1Y14_00860)	comGA/cglA/cilD	137873..138814 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
R1Y14_RS00865 (R1Y14_00865)	-	138890..139255 (-)	366	WP_000286415.1	DUF1033 family protein	-
R1Y14_RS00870 (R1Y14_00870)	-	139406..140464 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17972.67 Da
• Isoelectric Point: 9.6092

>NTDB_id=893210 R1Y14_RS00835 WP_000250534.1 135495..135956(-) (comGF/cglF) [Streptococcus pneumoniae strain ST62]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=893210 R1Y14_RS00835 WP_000250534.1 135495..135956(-) (comGF/cglF) [Streptococcus pneumoniae strain ST62]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGACTCAAATCTGTACGGATTACAGAGGACAATCAACTGGTTCGCTTTCATT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	100	100	1
comGF/cglF	Streptococcus pneumoniae D39	100	100	1
comGF/cglF	Streptococcus pneumoniae R6	100	100	1
comGF/cglF	Streptococcus pneumoniae TIGR4	100	100	1
comGF/cglF	Streptococcus mitis SK321	90.85	100	0.909
comGF/cglF	Streptococcus mitis NCTC 12261	89.542	100	0.895