Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ABDT56_RS15580 Genome accession   NZ_CP152467
Coordinates   3170009..3170668 (+) Length   219 a.a.
NCBI ID   WP_001221495.1    Uniprot ID   P52076
Organism   Escherichia coli strain Sel(aux star)     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3165009..3175668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABDT56_RS15555 ygiS 3166292..3167899 (-) 1608 WP_001295629.1 ABC transporter substrate-binding protein -
  ABDT56_RS15560 mqsA 3168032..3168427 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  ABDT56_RS15565 mqsR 3168429..3168725 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  ABDT56_RS15570 ygiV 3168930..3169412 (-) 483 WP_000183505.1 GyrI-like domain-containing protein -
  ABDT56_RS15575 ygiW 3169465..3169857 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  ABDT56_RS15580 ciaR 3170009..3170668 (+) 660 WP_001221495.1 quorum sensing response regulator transcription factor QseB Regulator
  ABDT56_RS15585 qseC 3170665..3172014 (+) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  ABDT56_RS15590 ygiZ 3172060..3172392 (-) 333 WP_000917684.1 DUF2645 family protein -
  ABDT56_RS15595 mdaB 3172711..3173292 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  ABDT56_RS15600 ygiN 3173323..3173637 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  ABDT56_RS15605 parE 3173685..3175577 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24677.59 Da        Isoelectric Point: 6.9850

>NTDB_id=892860 ABDT56_RS15580 WP_001221495.1 3170009..3170668(+) (ciaR) [Escherichia coli strain Sel(aux star)]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLSRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=892860 ABDT56_RS15580 WP_001221495.1 3170009..3170668(+) (ciaR) [Escherichia coli strain Sel(aux star)]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGTCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P52076

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361