Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   R1T10_RS02190 Genome accession   NZ_CP136807
Coordinates   401130..401579 (+) Length   149 a.a.
NCBI ID   WP_002221685.1    Uniprot ID   A1KW94
Organism   Neisseria meningitidis NMB     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 402276..403617 401130..401579 flank 697
Genomic island 401130..414599 401130..401579 within 0


Gene organization within MGE regions


Location: 401130..414599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1T10_RS02190 comP 401130..401579 (+) 450 WP_002221685.1 type IV pilin protein Machinery gene
  R1T10_RS02195 - 401740..402063 (-) 324 WP_202052896.1 5'-nucleotidase -
  R1T10_RS02200 - 402276..402626 (+) 351 Protein_413 IS5/IS1182 family transposase -
  R1T10_RS02205 - 402652..403617 (-) 966 WP_002223479.1 IS30-like element IS1655 family transposase -
  R1T10_RS02210 - 403707..403832 (+) 126 Protein_415 IS5/IS1182 family transposase -
  R1T10_RS02215 - 404238..405293 (+) 1056 WP_002221681.1 DNA cytosine methyltransferase -
  R1T10_RS02220 - 405307..406953 (+) 1647 WP_002214929.1 TIGR02391 family protein -
  R1T10_RS02225 - 406957..407379 (+) 423 WP_002214928.1 very short patch repair endonuclease -
  R1T10_RS02230 - 407402..409264 (-) 1863 Protein_419 DUF3418 domain-containing protein -
  R1T10_RS02235 - 409661..410839 (-) 1179 Protein_420 DUF3418 domain-containing protein -
  R1T10_RS02240 lpt3 410941..412518 (-) 1578 WP_002226775.1 lipooligosaccharide phosphoethanolamine transferase -
  R1T10_RS02245 - 412730..412912 (-) 183 WP_002223144.1 hypothetical protein -
  R1T10_RS02250 - 412956..414599 (-) 1644 WP_002223143.1 AAA family ATPase -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16848.83 Da        Isoelectric Point: 9.7951

>NTDB_id=892834 R1T10_RS02190 WP_002221685.1 401130..401579(+) (comP) [Neisseria meningitidis NMB]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYIEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=892834 R1T10_RS02190 WP_002221685.1 401130..401579(+) (comP) [Neisseria meningitidis NMB]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATATTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KW94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

99.329

100

0.993
  comP Neisseria meningitidis 8013

98.658

100

0.987
  comP Neisseria subflava NJ9703

48.98

98.658

0.483