Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RYQ61_RS08260 Genome accession   NZ_CP136799
Coordinates   1636418..1637764 (+) Length   448 a.a.
NCBI ID   WP_003072859.1    Uniprot ID   A0A3R9KNQ5
Organism   Streptococcus intermedius strain XH2169     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1631418..1642764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RYQ61_RS08230 (RYQ61_08230) - 1632308..1633267 (+) 960 WP_021002774.1 ROK family glucokinase -
  RYQ61_RS08235 (RYQ61_08235) rplS 1633417..1633764 (+) 348 WP_003024326.1 50S ribosomal protein L19 -
  RYQ61_RS08245 (RYQ61_08245) - 1634009..1634749 (+) 741 WP_102568042.1 alpha/beta hydrolase -
  RYQ61_RS08250 (RYQ61_08250) - 1635049..1635492 (+) 444 WP_020998689.1 hypothetical protein -
  RYQ61_RS08255 (RYQ61_08255) ciaR 1635754..1636428 (+) 675 WP_003036714.1 response regulator transcription factor Regulator
  RYQ61_RS08260 (RYQ61_08260) ciaH 1636418..1637764 (+) 1347 WP_003072859.1 cell wall metabolism sensor histidine kinase WalK Regulator
  RYQ61_RS08265 (RYQ61_08265) - 1638040..1639488 (-) 1449 WP_172964128.1 alpha-amylase -
  RYQ61_RS08270 (RYQ61_08270) - 1639867..1640367 (-) 501 WP_102568040.1 DNA topology modulation protein -
  RYQ61_RS08275 (RYQ61_08275) rpsT 1640432..1640668 (-) 237 WP_003072853.1 30S ribosomal protein S20 -
  RYQ61_RS08280 (RYQ61_08280) coaA 1640737..1641657 (-) 921 WP_102568039.1 type I pantothenate kinase -
  RYQ61_RS08285 (RYQ61_08285) - 1641750..1642343 (+) 594 WP_003076784.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 50910.65 Da        Isoelectric Point: 10.1689

>NTDB_id=892746 RYQ61_RS08260 WP_003072859.1 1636418..1637764(+) (ciaH) [Streptococcus intermedius strain XH2169]
MLNKLKKAWYADDFSYFIRNFGIFTLIFSAMTLIIIQVMRSSLYTTVDNNLKSLSQDSASVINLALARKVGLEQKSENGE
PKSGTADKELTDKPNVSANTEVILFDKNYKSIITSNNFLGFNKLSFNSKQLDRIRQIQVKSNYGREETYRMVLFQVKLPN
LETNVKYAAVFINISQLEQTSQNHEQLIVVVMISFWGISLIASVYLARVSVKPLLESIQKQKSFVENASHELRTPLAVLQ
NRLETLFRKPEATIMESSESIASSLDEVRNMKMLTTNLLNLARRDDGIKPEIGDIEPNFFNTTFTNYEMVATENGKVFRF
DNRIHRVIKTDKTLLKQLMTILFDNALKYTDEDGVIELTISANDRNLFLKVSDNGPGISTADKKKIFDRFYRVDKARTRQ
TGGFGLGLSLAKQITEALKGTITVKDNKPKGTVFEVKIAIRTDNKKKK

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=892746 RYQ61_RS08260 WP_003072859.1 1636418..1637764(+) (ciaH) [Streptococcus intermedius strain XH2169]
ATGCTGAATAAACTAAAAAAAGCATGGTATGCGGATGATTTTTCTTATTTCATTCGCAATTTTGGTATTTTTACTCTCAT
TTTCTCAGCTATGACTTTGATTATCATTCAAGTTATGCGCTCAAGCCTTTATACAACGGTAGATAATAATTTAAAAAGCT
TGAGTCAAGATTCGGCTTCTGTGATTAATTTAGCGCTTGCTCGAAAAGTAGGGCTAGAGCAAAAGTCAGAAAATGGAGAA
CCTAAAAGCGGAACAGCTGATAAAGAGCTGACAGATAAACCAAATGTGAGTGCCAATACAGAAGTTATTTTATTTGATAA
GAATTATAAATCAATTATTACAAGCAATAATTTTTTAGGGTTTAATAAACTTTCCTTTAATAGCAAGCAATTAGATCGTA
TTCGTCAAATTCAAGTAAAAAGCAATTATGGCCGAGAAGAAACCTATCGGATGGTTTTGTTTCAAGTGAAATTGCCTAAT
TTAGAAACCAATGTCAAATACGCAGCAGTTTTTATCAATATTAGCCAATTGGAACAAACTAGTCAAAACCATGAACAGTT
GATTGTAGTTGTGATGATTAGTTTCTGGGGAATTTCCTTGATTGCTAGTGTCTATCTTGCGCGAGTAAGTGTCAAACCGC
TTTTGGAAAGTATTCAAAAACAAAAGAGCTTTGTCGAAAATGCTAGTCATGAATTACGCACACCTTTAGCCGTTTTGCAA
AATCGTTTGGAGACTTTGTTTAGAAAACCAGAAGCTACCATTATGGAATCGAGTGAAAGCATCGCTTCTAGTTTAGATGA
AGTGCGAAACATGAAAATGTTGACAACGAACTTACTTAATTTAGCACGGCGTGATGATGGGATTAAACCAGAGATTGGTG
ATATTGAACCCAATTTCTTTAATACGACCTTTACGAACTATGAAATGGTTGCCACAGAAAATGGAAAAGTTTTTCGATTT
GACAATAGGATTCACCGTGTGATAAAAACGGATAAAACCTTACTGAAGCAATTGATGACTATCTTGTTTGATAATGCCTT
GAAATATACAGACGAAGACGGTGTGATTGAATTGACAATCTCTGCAAATGATCGAAATTTGTTTTTGAAGGTTTCGGATA
ATGGTCCAGGGATTAGTACAGCAGATAAGAAAAAGATTTTTGATCGTTTTTATCGTGTTGATAAAGCACGGACTCGACAG
ACAGGTGGTTTTGGTTTAGGGTTGTCGCTTGCAAAGCAAATCACAGAAGCTCTTAAAGGAACTATTACAGTGAAAGATAA
TAAACCGAAAGGGACTGTTTTTGAAGTAAAGATTGCGATTCGAACGGATAATAAAAAGAAAAAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(331-438)

His Kinase A (phospho-acceptor) domain (HisKA)

(222-287)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9KNQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

70.312

100

0.703
  ciaH Streptococcus pneumoniae D39

70.312

100

0.703
  ciaH Streptococcus pneumoniae R6

70.312

100

0.703
  ciaH Streptococcus pneumoniae TIGR4

70.312

100

0.703
  ciaH Streptococcus mutans UA159

55.708

97.768

0.545