Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   RSK81_RS09850 Genome accession   NZ_CP135591
Coordinates   1988445..1989743 (-) Length   432 a.a.
NCBI ID   WP_315686663.1    Uniprot ID   A0AA96SKN4
Organism   Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1983445..1994743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RSK81_RS09840 (RSK81_09840) hpf 1987159..1987701 (-) 543 WP_002903257.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  RSK81_RS09845 (RSK81_09845) - 1987783..1988448 (-) 666 WP_125378630.1 ComF family protein -
  RSK81_RS09850 (RSK81_09850) comFA/cflA 1988445..1989743 (-) 1299 WP_315686663.1 DEAD/DEAH box helicase Machinery gene
  RSK81_RS09855 (RSK81_09855) - 1989799..1990431 (+) 633 WP_315686665.1 YigZ family protein -
  RSK81_RS09860 (RSK81_09860) cysK 1990532..1991461 (+) 930 WP_002893488.1 cysteine synthase A -
  RSK81_RS09865 (RSK81_09865) - 1991566..1991928 (-) 363 WP_002926507.1 S1 RNA-binding domain-containing protein -
  RSK81_RS09870 (RSK81_09870) - 1991928..1993328 (-) 1401 WP_002934595.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RSK81_RS09875 (RSK81_09875) - 1993368..1994000 (-) 633 WP_002926512.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49525.20 Da        Isoelectric Point: 8.4674

>NTDB_id=887045 RSK81_RS09850 WP_315686663.1 1988445..1989743(-) (comFA/cflA) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MLELQDCLGRIFTENQLEPSLRAKAKEIPSIREEKGKLRCGRCNSLIERENQLPVGAYYCRECLLLGRVRSDQKHYYFPQ
ENFPKNKVLKWQGQLTEFQGKVSRGLLDALEKRQNTLVHAVTGAGKTEMIYQVLARVIDRGGSVCLASPRIDVCLELYRR
LKEDFSCEIALLHGESEAYFRSPLVIATTHQLLKFHQAFDLLIVDEVDAFPYVDNPMLYHAVERSVKEDATTIFLTATST
DELDKRVQKGELKRLSLPRRFHGNPLTIPQKVWLSDFQKHLQKKKIAPKLLNYIEKQRETQFPLLIFAAEIQRGEDFAQA
LQIALPDEKLAFVASTTENRLEIVEQFRRKEITILVTTTILERGVTFPGVDVFVLEANHRLFSRSALVQISGRVGRSMDR
STGQLLFFHDGTTLAMEKAIREMRDMNTEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=887045 RSK81_RS09850 WP_315686663.1 1988445..1989743(-) (comFA/cflA) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGTTAGAGTTACAAGATTGTTTAGGACGGATATTTACAGAAAATCAGTTAGAGCCTAGCTTGCGAGCAAAAGCAAAAGA
AATTCCCAGTATCCGAGAAGAAAAAGGCAAGCTCCGCTGCGGACGCTGCAACAGCTTGATTGAACGAGAAAATCAGCTAC
CTGTTGGAGCTTATTATTGTAGAGAATGCTTACTATTGGGTCGGGTACGGAGTGACCAAAAACACTACTATTTTCCTCAA
GAGAATTTTCCTAAAAATAAAGTGCTTAAATGGCAGGGGCAACTGACAGAGTTTCAGGGGAAGGTCTCCAGAGGCTTACT
TGATGCGCTAGAGAAAAGACAGAATACGTTAGTGCATGCTGTTACTGGCGCTGGAAAGACAGAAATGATTTACCAAGTGC
TTGCAAGAGTTATTGATAGAGGAGGTTCTGTCTGTTTGGCCAGTCCGCGGATTGATGTTTGTTTAGAACTTTATCGGCGC
CTTAAAGAAGATTTTTCTTGTGAAATAGCCCTTCTGCATGGGGAATCAGAAGCTTATTTTCGCAGCCCCTTGGTGATTGC
CACCACCCATCAGCTCTTGAAATTTCATCAAGCATTTGATTTGCTGATTGTGGATGAGGTAGATGCTTTTCCTTATGTGG
ATAATCCCATGCTGTATCACGCTGTAGAGCGTTCTGTGAAAGAGGATGCTACAACTATTTTTCTGACAGCCACTTCCACA
GATGAACTGGATAAAAGAGTTCAAAAAGGTGAGTTGAAACGCCTGAGTCTTCCCAGAAGATTTCATGGTAATCCCTTGAC
CATCCCTCAGAAAGTTTGGTTATCCGATTTTCAAAAACATCTTCAGAAGAAGAAAATAGCACCTAAACTTTTGAACTATA
TAGAAAAACAGAGGGAGACCCAATTTCCTCTCTTAATATTTGCTGCAGAAATTCAAAGAGGAGAGGATTTTGCTCAGGCT
TTACAGATTGCTCTGCCGGATGAAAAGCTGGCTTTTGTCGCCTCCACAACAGAAAATCGTCTAGAGATTGTCGAGCAGTT
TCGTCGCAAGGAGATCACTATTTTGGTGACAACGACTATCTTAGAGCGTGGAGTAACCTTTCCTGGCGTGGATGTTTTTG
TCTTGGAAGCCAATCATCGTTTGTTCAGTCGTAGTGCTCTGGTTCAGATTTCAGGCCGAGTTGGCCGTAGTATGGATAGA
TCGACTGGACAGTTGCTATTTTTTCATGATGGGACTACCCTTGCTATGGAAAAAGCAATTCGAGAAATGAGAGATATGAA
TACGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(109-244)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

70.726

98.843

0.699
  comFA/cflA Streptococcus pneumoniae D39

70.726

98.843

0.699
  comFA/cflA Streptococcus pneumoniae R6

70.726

98.843

0.699
  comFA/cflA Streptococcus pneumoniae TIGR4

70.492

98.843

0.697
  comFA/cflA Streptococcus mitis NCTC 12261

70.588

98.38

0.694
  comFA/cflA Streptococcus mitis SK321

69.412

98.38

0.683
  comFA Lactococcus lactis subsp. cremoris KW2

54.774

92.13

0.505
  comFA Latilactobacillus sakei subsp. sakei 23K

37.85

99.074

0.375
  comFA Bacillus subtilis subsp. subtilis str. 168

37.956

95.139

0.361