Detailed information NTG0885296

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QN325_RS10115
• Genome accession: NZ_CP135101
• Coordinates: 1983083..1984156 (-)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain HU13/21
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1978083..1989156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN325_RS10095 (QN325_10075)	-	1979357..1979872 (-)	516	WP_000919802.1	VanZ family protein	-
QN325_RS10100 (QN325_10080)	rlmN	1979872..1980978 (-)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QN325_RS10105 (QN325_10085)	-	1981029..1981607 (-)	579	WP_001224500.1	YutD family protein	-
QN325_RS10110 (QN325_10090)	-	1981676..1983008 (-)	1333	Protein_1929	bifunctional metallophosphatase/5'-nucleotidase	-
QN325_RS10115 (QN325_10095)	sepM	1983083..1984156 (-)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
QN325_RS10120 (QN325_10100)	coaD	1984146..1984631 (-)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
QN325_RS10125 (QN325_10105)	-	1984628..1984918 (-)	291	WP_000384889.1	hypothetical protein	-
QN325_RS10130 (QN325_10110)	rsmD	1984930..1985469 (-)	540	WP_001266830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QN325_RS10135 (QN325_10115)	-	1985599..1986048 (+)	450	WP_000592263.1	thiol reductase thioredoxin	-
QN325_RS10140 (QN325_10120)	asnA	1986093..1987085 (-)	993	WP_000748017.1	aspartate--ammonia ligase	-
QN325_RS10145 (QN325_10125)	-	1987199..1988263 (-)	1065	WP_000021309.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=885296 QN325_RS10115 WP_000796095.1 1983083..1984156(-) (sepM) [Streptococcus agalactiae strain HU13/21]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=885296 QN325_RS10115 WP_000796095.1 1983083..1984156(-) (sepM) [Streptococcus agalactiae strain HU13/21]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658