Detailed information NTG0884957

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: RMQ61_RS00385
• Genome accession: NZ_CP135090
• Coordinates: 65447..66364 (+)
• Length: 305 a.a.
• NCBI ID: WP_024383080.1
• Uniprot ID: A0A116P322
• Organism: Streptococcus suis strain ID48908
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	63880..65082	65447..66364	flank	365

Gene organization within MGE regions

Location: 63880..66364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMQ61_RS00380 (RMQ61_00380)	-	63880..65082 (-)	1203	WP_313921432.1	IS110 family transposase	-
RMQ61_RS00385 (RMQ61_00385)	comR	65447..66364 (+)	918	WP_024383080.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 305 a.a.
• Molecular weight: 36253.31 Da
• Isoelectric Point: 4.6318

>NTDB_id=884957 RMQ61_RS00385 WP_024383080.1 65447..66364(+) (comR) [Streptococcus suis strain ID48908]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYDHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR

Nucleotide

• Length: 918 bp

>NTDB_id=884957 RMQ61_RS00385 WP_024383080.1 65447..66364(+) (comR) [Streptococcus suis strain ID48908]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTACTATGATGAATTGCCTGAGGAGGAGAAGATAGTTGTAGATACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATGATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAGTATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix domain (HTH_31) (5-60)

3D structure

• AlphaFold DB: A0A116P322

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis D9	99.672	100	0.997
comR	Streptococcus suis P1/7	62.126	98.689	0.613
comR	Streptococcus suis 05ZYH33	62.126	98.689	0.613
comR	Streptococcus mutans UA159	37.333	98.361	0.367