Detailed information NTG0884852

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: RMP67_RS00485
• Genome accession: NZ_CP135087
• Coordinates: 92190..93107 (+)
• Length: 305 a.a.
• NCBI ID: WP_024383080.1
• Uniprot ID: A0A116P322
• Organism: Streptococcus suis strain ID26102
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	90623..91825	92190..93107	flank	365

Gene organization within MGE regions

Location: 90623..93107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMP67_RS00480 (RMP67_00480)	-	90623..91825 (-)	1203	WP_313921432.1	IS110 family transposase	-
RMP67_RS00485 (RMP67_00485)	comR	92190..93107 (+)	918	WP_024383080.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 305 a.a.
• Molecular weight: 36253.31 Da
• Isoelectric Point: 4.6318

>NTDB_id=884852 RMP67_RS00485 WP_024383080.1 92190..93107(+) (comR) [Streptococcus suis strain ID26102]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYDHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR

Nucleotide

• Length: 918 bp

>NTDB_id=884852 RMP67_RS00485 WP_024383080.1 92190..93107(+) (comR) [Streptococcus suis strain ID26102]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTACTATGATGAATTGCCTGAGGAGGAGAAGATAGTTGTAGATACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATGATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAGTATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix domain (HTH_31) (5-60)

3D structure

• AlphaFold DB: A0A116P322

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis D9	99.672	100	0.997
comR	Streptococcus suis P1/7	62.126	98.689	0.613
comR	Streptococcus suis 05ZYH33	62.126	98.689	0.613
comR	Streptococcus mutans UA159	37.333	98.361	0.367