Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   RMQ62_RS09050 Genome accession   NZ_CP135065
Coordinates   1872600..1873949 (+) Length   449 a.a.
NCBI ID   WP_002935841.1    Uniprot ID   G7SGQ2
Organism   Streptococcus suis strain ID24665     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1867600..1878949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ62_RS09025 (RMQ62_09025) - 1868711..1869370 (-) 660 WP_024402697.1 amino acid ABC transporter permease -
  RMQ62_RS09030 (RMQ62_09030) - 1869385..1870083 (-) 699 WP_013730248.1 amino acid ABC transporter permease -
  RMQ62_RS09035 (RMQ62_09035) - 1870098..1870937 (-) 840 WP_313681060.1 transporter substrate-binding domain-containing protein -
  RMQ62_RS09040 (RMQ62_09040) - 1870948..1871709 (-) 762 WP_024407012.1 amino acid ABC transporter ATP-binding protein -
  RMQ62_RS09045 (RMQ62_09045) micA 1871903..1872607 (+) 705 WP_004298854.1 response regulator YycF Regulator
  RMQ62_RS09050 (RMQ62_09050) micB 1872600..1873949 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RMQ62_RS09055 (RMQ62_09055) vicX 1873956..1874759 (+) 804 WP_024399908.1 MBL fold metallo-hydrolase Regulator
  RMQ62_RS09060 (RMQ62_09060) vga(F) 1875017..1876402 (+) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -
  RMQ62_RS09065 (RMQ62_09065) pbp2b 1876494..1878563 (+) 2070 WP_125183704.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51039.08 Da        Isoelectric Point: 4.5202

>NTDB_id=884749 RMQ62_RS09050 WP_002935841.1 1872600..1873949(+) (micB) [Streptococcus suis strain ID24665]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=884749 RMQ62_RS09050 WP_002935841.1 1872600..1873949(+) (micB) [Streptococcus suis strain ID24665]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAACGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCTTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGATCGTTACACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTAACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGCATTGATAATCAGGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTGTCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SGQ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635